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Assessment of guided lateral maxillary sinus lift procedure with simultaneous implant placement using stereolithographic surgical guide: a randomized controlled clinical study. 评估引导上颌外侧窦提升术与同时种植体放置立体骨成像手术指南:一项随机对照临床研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-17 DOI: 10.1007/s10006-025-01399-3
Wael Hussein, Ahmed Younis, Ahmad Elrawdy, Mohamed ElSholkamy

Aim: The aim of this study is to assess the efficacy of the stereolithographic surgical guide in reducing intraoperative and postoperative complication during lateral sinus lift operation.

Materials and methods: A parallel randomized controlled prospective clinical study was conducted on fourteen patients requiring thirty dental implants in the posterior maxilla and diagnosed with reduced vertical bone height. Lateral Maxillary Sinus Lift procedure with simultaneous implant placement was performed to all patients. Stereolithographic surgical guides for lateral window osteotomy and implant drilling and placement were used in the study group, while lateral osteotomy and implant drilling and placement was done freehand in the control group. A cone beam computed tomography was taken immediately and six months post-sinus lifting. Intraoperative and postoperative complications were assessed, pain and edema were assessed using visual analogue scale and vertical bone was assessed using fusion module of cone beam computed tomography.

Results: All dental implants demonstrated high survival rates with no statistically significant difference observed in intraoperative or postoperative complications. In terms of new vertical bone gain, both groups exhibited satisfactory and successful outcomes. Concerning pain, there was no statistically significant difference between the two groups except after two days, the study group showed statistically significantly lower pain score than the control group. While regarding the severity of edema, the study group showed statistically significantly higher prevalence of moderate and severe edema than control group which showed higher prevalence of mild edema.

Conclusion: According to the current study it has been concluded that there was no remarkable difference between the outcomes of both methods. The study protocol and its consent form were approved by the ethical committee of Suez Canal University (No.432/2021); and registered retrospectively on 23 April 2024 on PACTR (PACTR20240875463218) (pactr.samrc.ac.za/TrialDisplay.aspx?TrialID = 30442).

目的:本研究的目的是评估立体骨成像手术指南在减少侧窦提升术中及术后并发症方面的效果。材料与方法:采用平行随机对照前瞻性临床研究,对14例诊断为垂直骨高度降低,需要在后上颌种植30颗牙的患者进行研究。所有患者均行上颌外侧窦提升术并同时植入种植体。研究组采用侧窗截骨和种植体钻孔放置的立体骨成像手术指南,对照组采用徒手进行侧窗截骨和种植体钻孔放置。在鼻窦提升6个月后立即进行锥形束计算机断层扫描。评估术中及术后并发症,使用视觉模拟量表评估疼痛和水肿,使用锥束计算机断层融合模块评估垂直骨。结果:所有种植体的成活率均较高,术中及术后并发症无统计学差异。在垂直骨生长方面,两组均表现出满意和成功的结果。在疼痛方面,两组间差异无统计学意义,但两天后,研究组疼痛评分低于对照组,差异有统计学意义。而在水肿的严重程度上,研究组中重度水肿的患病率高于对照组,对照组轻度水肿的患病率高于对照组,有统计学意义。结论:根据目前的研究,两种方法的结果没有显著差异。研究方案及其同意书经苏伊士运河大学伦理委员会批准(No.432/2021);并于2024年4月23日在PACTR上回顾性注册(PACTR20240875463218) (PACTR .samrc.ac.za/TrialDisplay.aspx?TrialID = 30442)。
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引用次数: 0
Impact of buccal fat pad removal on electrical activity of masseter, temporal, and buccinator muscles, anxiety, aesthetic satisfaction, and quality of life. 颊脂肪垫去除对咬肌、颞肌和颊肌电活动、焦虑、审美满意度和生活质量的影响。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-14 DOI: 10.1007/s10006-025-01396-6
Leonardo de Oliveira Segura, Clóvis Lamartine de Moraes Melo Neto, Luisa de Oliveira Costa, Fernanda Pereira de Caxias, Isabela Caroline de Sousa Ervolino, Tiburtino José Lima Neto, Emily Vivianne Freitas da Silva, Juliana Dela Líbera, Leonardo P Faverani, Marcelo Coelho Goiato, Daniela Micheline Dos Santos, Marcella Santos Januzzi, Karina Helga Leal Turcio

Purpose: To evaluate the electromyographic activity of the masseter, temporal, and buccinator muscles, as well as anxiety levels, aesthetic satisfaction, and quality of life following bichectomy.

Methods: Nine patients were included. Electromyography of the masseter, anterior temporal, and buccinator muscles was performed, along with assessment of the number of masticatory cycles and mastication time until swallowing. Anxiety levels (Generalized Anxiety Disorder-7), the impact of surgery on quality of life (Glasgow Benefit Inventory - GBI), and patient aesthetic satisfaction were evaluated using questionnaires. Assessments were conducted before surgery (T0), 60 days after surgery (T1), and 120 days after surgery (T2). A 2-way repeated measures ANOVA was used and when the analyzed data were not considered normal, the Friedman test was used (p < 0.05).

Results: The activity of the masseter and buccinator muscles increased significantly after 30 days (T1) and 120 days (T2) after bichectomy compared to T0. The number of chewing cycles and time until swallowing and anxiety did not change significantly over time. Aesthetic satisfaction increased significantly after 30 days.

Conclusion: Removing the main body of the Bichat ball increased the electrical activity of the masseter and buccinator muscles during chewing of the tested foods. The participants' anxiety level over time was considered clinically acceptable. Buccal fat pad removal did not influence the number of chewing cycles and chewing time until swallowing. Aesthetic satisfaction increased 60 days after bichectomy. After 120 days of buccal fat pad removal, there was an improvement in the quality of life of the individuals.

目的:评估双肺切除术后咬肌、颞肌和颊肌的肌电图活动,以及焦虑水平、审美满意度和生活质量。方法:9例患者。检查咬肌、颞前肌和颊肌的肌电图,并评估咀嚼循环次数和咀嚼至吞咽的时间。焦虑水平(广泛性焦虑障碍-7)、手术对生活质量的影响(格拉斯哥福利量表- GBI)和患者审美满意度通过问卷进行评估。术前(T0)、术后60天(T1)、术后120天(T2)分别进行评估。使用双侧重复测量方差分析,当分析数据不正常时,使用Friedman检验(p)。结果:与T0相比,双侧切除术后30天(T1)和120天(T2)咬肌和颊肌的活动显著增加。咀嚼循环的次数和时间直到吞咽和焦虑没有明显变化。30天后审美满意度显著提高。结论:去除Bichat球主体后,咀嚼食物时咬肌和颊肌的电活动增加。随着时间的推移,参与者的焦虑水平被认为是临床可接受的。口腔脂肪垫去除对咀嚼次数和咀嚼时间无影响。双侧切除术后60天审美满意度提高。在去除口腔脂肪垫120天后,患者的生活质量得到了改善。
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引用次数: 0
Assessment of the prevalence of nasal deviation in patients requiring orthognathic surgery: association with maxillary, mandibular, or chin asymmetry. 评估需要正颌手术的患者鼻部偏曲的患病率:与上颌、下颌或下巴不对称的关系。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-13 DOI: 10.1007/s10006-025-01398-4
Federico Hernández-Alfaro, Oscar Saavedra, Gonzalo Botella-Casas, Mahdi Ghuloom, Maria Giralt-Hernando, Adaia Valls-Ontañón

Purpose: Identifying nasal deviation in patients requiring orthognathic surgery is critical for developing an accurate treatment plan, particularly in the axial plane. This study aimed to evaluate the prevalence and degree of nasal and septal deviation in patients requiring orthognathic surgery, and to assess their relationship with maxillary, mandibular, and chin asymmetries, as well as dento-skeletal class.

Material and methods: A retrospective study was conducted on patients who required orthognathic surgery between July 2020 and February 2021. Exclusion criteria included congenital craniofacial anomalies, history of mandibular condylar hyperplasia, or prior rhino-septoplasty procedures.

Results: Of the 103 patients studied, 97.1% exhibited some degree of nasal deviation, and all presented with septal deviation. Nasal septum deviation correlated significantly with nasal tip deviation (r = 0.44, p < 0.001) and dorsum deviation (r = 0.41, p < 0.001). A combination of nasal, maxillary, mandibular, and chin deviations was present in 77.3%, 83.5%, and 88.3% of patients, respectively. Significant correlations were found between the directions of maxillary (r = 0.21, p = 0.032), mandibular (r = 0.25, p = 0.012), and chin deviations (r = 0.19, p = 0.050).

Conclusions: This study highlights that nasal and septal deviations are highly prevalent in patients requiring orthognathic surgery, and their accurate diagnosis is essential for successful orthognathic diagnosis and surgical planning. These findings support the inclusion of nasal assessments in the treatment plans for orthognathic surgery patients.

目的:识别需要正颌手术的患者的鼻偏曲对于制定准确的治疗计划至关重要,特别是在轴向面。本研究旨在评估需要正颌手术的患者鼻中隔偏曲的患病率和程度,并评估其与上颌、下颌和下巴不对称以及牙齿-骨骼分类的关系。材料和方法:对2020年7月至2021年2月期间需要进行正颌手术的患者进行回顾性研究。排除标准包括先天性颅面异常、下颌髁增生史或既往鼻中隔成形术。结果:103例患者中97.1%表现出不同程度的鼻偏曲,且均表现为鼻中隔偏曲。结论:本研究强调鼻中隔和鼻中隔偏曲在正颌手术患者中非常普遍,其准确诊断对于成功的正颌诊断和手术计划至关重要。这些发现支持将鼻腔评估纳入正颌手术患者的治疗计划。
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引用次数: 0
Influence of crown-implant ratio on photofuntcionalized short implants success rates: 5 year follow-up prospective study. 冠状种植体比例对光功能短种植体成功率的影响:5年随访前瞻性研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-13 DOI: 10.1007/s10006-025-01395-7
Naira Ghambaryan, Curd Bollen, Gagik Hakobyan

Objective: To evaluate the influence of crown-to-implant ratio(C/I) on marginal bone level changes and survival rate of implants during function.

Methods: The study included 68 patients with completely or partial edentulous and severe vertical bone atrophy, which were restored with a single crown(46) or a partial fixed(48) denture supported by 152 short implants. Implants were divided into three groups according to the C/I ratio (1.5:1, 1,75:1, 2:1). The results were evaluated: failures of the implant, any complications, implants marginal bone loss (MBL), implants success rates the follow up for 5 years. MBL was assessed by taking x-rays after restoration fixation, after 1,3,5 years post operatively.

Results: During implantation and in the post-implantation period, no serious biological or prosthetic complications were recorded. After 1 years in Group 1 mean MBL 0.86 ± 0.4 mm, after 3 years 0,98 ± 0.2 mm), after 5 years 1.05 ± 0.3 mm. After 1 years in Group 2 mean MBL 0.97 ± 0.3 mm, after 3 years 1,07 ± 0.4 mm), after 5 years MBL was 1.12 ± 0.6 mm.Аfter 1 years in Group 3 mean MBL 1,08 ± 0.6 mm, after 3 years 1,19 ± 0.2 mm, after 5 years MBL was 1.27 ± 0.3 mm. Short implants cumulative success of implantation after 5 years was 97.8% for group 1, 97.6% for group 2, and 97.3% for group 3. Patients were satisfied with the results of treatment.

Conclusions: The study showed that different C/I ratios of short implants did not affect the survival rate and their use can be considered favorable and completely justified.

Clinical trial number: Not applicable.

目的:探讨冠与种植体之比(C/I)对种植体功能期间边缘骨水平变化及成活率的影响。方法:对68例全牙或部分无牙伴严重垂直骨萎缩患者,采用单冠义齿(46例)或部分固定义齿(48例),并采用152根短种植体进行修复。根据C/I比(1.5:1、1、75:1、2:1)将种植体分为三组。结果评估:种植体失败,并发症,种植体边缘骨丢失(MBL),种植体成功率,随访5年。术后1年、3年、5年分别用x线片评估MBL。结果:种植期间及种植后未发生严重的生物或假体并发症。1年后1组平均MBL 0.86±0.4 mm, 3年后0.98±0.2 mm, 5年后1.05±0.3 mm。2组1年后MBL平均为0.97±0.3 mm, 3年后为1,07±0.4 mm, 5年后MBL为1.12±0.6 mm.Аfter 3组1年后MBL平均为1,08±0.6 mm, 3年后为1,19±0.2 mm, 5年后MBL为1.27±0.3 mm。短种植体5年后累计种植成功率1组为97.8%,2组为97.6%,3组为97.3%。患者对治疗效果满意。结论:研究表明,不同的C/I比例的短种植体不影响生存率,其使用是有利的,完全合理的。临床试验号:不适用。
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引用次数: 0
Clinical and radiographic features of temporomandibular joint in patients with facial asymmetry. 面部不对称患者颞下颌关节的临床及影像学特征。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-10 DOI: 10.1007/s10006-025-01400-z
Yoshio Otake, Shinnosuke Nogami, Yushi Ezoe, Yuki Sugai, Kyosuke Okuyama, Shizu Saito, Yuri Takeda, Kensuke Yamauchi

Purpose: The purpose of this study was to investigate characteristics of mandibular head morphology and temporomandibular joint (TMJ) disorders (TMDs) on the deviation side (DS) and non-deviation side (NDS) in patients with facial asymmetry (FA).

Methods: Thirty patients diagnosed with FA were enrolled. Preoperative and postoperative joint sound and pain were evaluated in terms of clinical symptoms, and pre- and postoperative mandibular head morphology factors shown by computed tomography. In addition, magnetic resonance imaging findings were used to evaluate preoperative joint disc position and joint effusion (JE).

Results: The patients included 12 (40.0%) males and 18 (60.0%) females, with a mean age of 25.8 years. There were no significant differences regarding clinical symptoms between patients affected on the DS and those on the NDS. Preoperatively, the DS group showed a total of 4 joints (13.3%) with mandibular condyle head deformity, while postoperatively those patients had 13 (43.3%) and the NDS group 2 (6.7%), indicating a significant difference for condyle head deformity between patients affected on DS and NDS before and after surgery. The score for JE was 1.1 ± 1.0 in the DS group and 0.6 ± 0.8 in the NDS group, a significant difference (P < 0.05).

Conclusion: As compared to the NDS, the DS in the present class III patients with FA showed a greater number of TMDs, such as condyle head deformity, disc displacement, and JE. It's important for surgeons and orthodontists to be aware of the possibility of TMDs on the DS in class III patients with FA when performing orthognathic surgery.

目的:探讨面部不对称(FA)患者的下颌头形态及偏侧(DS)和非偏侧(NDS)颞下颌关节(TMJ)紊乱(TMDs)的特点。方法:入选30例确诊为FA的患者。根据临床症状和计算机断层扫描显示的术前和术后下颌头形态因素评估术前和术后关节声音和疼痛。此外,磁共振成像结果用于评估术前关节盘位置和关节积液(JE)。结果:男性12例(40.0%),女性18例(60.0%),平均年龄25.8岁。DS组和NDS组患者的临床症状无显著差异。术前DS组共有4个关节(13.3%)出现下颌髁突头畸形,而术后DS组有13个关节(43.3%),NDS组2例(6.7%),说明DS组和NDS组患者的髁突头畸形在术前、术后差异有统计学意义。乙脑评分:DS组为1.1±1.0分,NDS组为0.6±0.8分,差异有统计学意义(P)。结论:与NDS相比,目前FA III类患者的DS表现出更多的TMDs,如髁突头畸形、椎间盘移位、乙脑。外科医生和正畸医生在进行正颌手术时,必须意识到III类FA患者在DS上发生TMDs的可能性。
{"title":"Clinical and radiographic features of temporomandibular joint in patients with facial asymmetry.","authors":"Yoshio Otake, Shinnosuke Nogami, Yushi Ezoe, Yuki Sugai, Kyosuke Okuyama, Shizu Saito, Yuri Takeda, Kensuke Yamauchi","doi":"10.1007/s10006-025-01400-z","DOIUrl":"10.1007/s10006-025-01400-z","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate characteristics of mandibular head morphology and temporomandibular joint (TMJ) disorders (TMDs) on the deviation side (DS) and non-deviation side (NDS) in patients with facial asymmetry (FA).</p><p><strong>Methods: </strong>Thirty patients diagnosed with FA were enrolled. Preoperative and postoperative joint sound and pain were evaluated in terms of clinical symptoms, and pre- and postoperative mandibular head morphology factors shown by computed tomography. In addition, magnetic resonance imaging findings were used to evaluate preoperative joint disc position and joint effusion (JE).</p><p><strong>Results: </strong>The patients included 12 (40.0%) males and 18 (60.0%) females, with a mean age of 25.8 years. There were no significant differences regarding clinical symptoms between patients affected on the DS and those on the NDS. Preoperatively, the DS group showed a total of 4 joints (13.3%) with mandibular condyle head deformity, while postoperatively those patients had 13 (43.3%) and the NDS group 2 (6.7%), indicating a significant difference for condyle head deformity between patients affected on DS and NDS before and after surgery. The score for JE was 1.1 ± 1.0 in the DS group and 0.6 ± 0.8 in the NDS group, a significant difference (P < 0.05).</p><p><strong>Conclusion: </strong>As compared to the NDS, the DS in the present class III patients with FA showed a greater number of TMDs, such as condyle head deformity, disc displacement, and JE. It's important for surgeons and orthodontists to be aware of the possibility of TMDs on the DS in class III patients with FA when performing orthognathic surgery.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"98"},"PeriodicalIF":1.8,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Instagram, a source of information and education about dental implants? Instagram,一个关于植牙的信息和教育来源?
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-07 DOI: 10.1007/s10006-025-01388-6
Franziska Kremer, Hans-Joachim Nickenig, Matthias Kreppel, Christian Linz, Max-Philipp Lentzen, Matthias Zirk

Purpose: The study assesses the teaching effect of social media on the topic of dental implants.

Methods: A sample of 400 Instagram posts were collected, 100 each for one of the following hashtags #dentalimplants, #implantdentisitry, #implantsurgery and #implantology. They were examined regarding their likes, comments, author (dentist or practice or clinic, dental technician, company, Instagram page, patient), gender, form of presentation (image + text, video, text, image) and purpose of the post. Afterwards all posts were divided into "excellent", "good", "moderate" and "poor" teaching effect regarding dental implantology by 6 different evaluators with different levels of training in dentistry. 400 Instagram posts were collected, each with hashtags related to dental implants, analyzed over a year.

Results: Men authored 48.5% of the posts, women 21.75%, and posts of unknown gender 29.75%. Images were the most common post format at 69.75%, while texts were the least at 0.75%. Dentists posted most frequently (76.5%), followed by dental technicians (11.5%), with educational posts (9.5%) being the least common purpose. Additionally, the evaluation of educational quality by six assessors showed that poor ratings were most common (76.7%), while excellent ratings were the least frequent (3.3%).

Conclusion: Currently, social media cannot be used to obtain quality information about dental implants. Nevertheless, social media as an information platform about health-related topics continues to grow and has an increasingly important role in the lives of patients and professionals.

目的:评估社交媒体对种植体主题的教学效果。方法:收集了400个Instagram帖子的样本,其中100个针对以下标签之一:#dentalimplant, # implantdentistry, #implantsurgery和#implantology。他们的点赞、评论、作者(牙医或诊所、牙科技师、公司、Instagram页面、患者)、性别、呈现形式(图像+文本、视频、文本、图像)和帖子的目的都被检查了。随后,由6名不同程度牙科培训水平的评价员将所有岗位的种植牙教学效果分为“优秀”、“良好”、“中等”和“较差”四个等级。他们在一年多的时间里收集了400个Instagram帖子,每个帖子都有与植牙相关的标签。结果:男性帖子占48.5%,女性帖子占21.75%,性别不明的帖子占29.75%。图片是最常见的帖子格式,占69.75%,而文字最少,占0.75%。最常张贴的是牙医(76.5%),其次是牙科技师(11.5%),而教育类(9.5%)则是最不常见的张贴目的。另外,6名评价官对教育质量的评价结果显示,评价差的最多(76.7%),评价优的最少(3.3%)。结论:目前社会媒体还不能很好地获取种植体相关的优质信息。然而,社交媒体作为健康相关话题的信息平台不断发展,在患者和专业人员的生活中发挥着越来越重要的作用。
{"title":"Instagram, a source of information and education about dental implants?","authors":"Franziska Kremer, Hans-Joachim Nickenig, Matthias Kreppel, Christian Linz, Max-Philipp Lentzen, Matthias Zirk","doi":"10.1007/s10006-025-01388-6","DOIUrl":"10.1007/s10006-025-01388-6","url":null,"abstract":"<p><strong>Purpose: </strong>The study assesses the teaching effect of social media on the topic of dental implants.</p><p><strong>Methods: </strong>A sample of 400 Instagram posts were collected, 100 each for one of the following hashtags #dentalimplants, #implantdentisitry, #implantsurgery and #implantology. They were examined regarding their likes, comments, author (dentist or practice or clinic, dental technician, company, Instagram page, patient), gender, form of presentation (image + text, video, text, image) and purpose of the post. Afterwards all posts were divided into \"excellent\", \"good\", \"moderate\" and \"poor\" teaching effect regarding dental implantology by 6 different evaluators with different levels of training in dentistry. 400 Instagram posts were collected, each with hashtags related to dental implants, analyzed over a year.</p><p><strong>Results: </strong>Men authored 48.5% of the posts, women 21.75%, and posts of unknown gender 29.75%. Images were the most common post format at 69.75%, while texts were the least at 0.75%. Dentists posted most frequently (76.5%), followed by dental technicians (11.5%), with educational posts (9.5%) being the least common purpose. Additionally, the evaluation of educational quality by six assessors showed that poor ratings were most common (76.7%), while excellent ratings were the least frequent (3.3%).</p><p><strong>Conclusion: </strong>Currently, social media cannot be used to obtain quality information about dental implants. Nevertheless, social media as an information platform about health-related topics continues to grow and has an increasingly important role in the lives of patients and professionals.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"97"},"PeriodicalIF":1.8,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cemento-osseous dysplasia: a multi-centre analysis of surgical management. 骨水泥发育不良:手术治疗的多中心分析。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-07 DOI: 10.1007/s10006-025-01394-8
Fadi Titinchi, Naser Alturki, Jean Morkel, Salem Alkaabi, Kathryn Taylor

Purpose: Cemento-osseous dysplasia (COD) is a fibro-osseous lesion whose management is highly controversial in the literature. Due to scarcity of comprehensive studies on its management, the aim of this study was to analyse its management and develop a treatment protocol.

Methods: A multi-centre retrospective cohort analysis was conducted at two tertiary referral hospitals on 124 patients diagnosed with COD from 2005 to 2023. Demographic, clinical, and radiological data were analysed and correlated with treatment methods. Post-operative complications such as osteomyelitis or pathological fracture were documented along with follow-up visits to evaluate the need for further treatment. Data was analysed using Student's t-test and Fisher's exact test. Statistical significance was set at P < 0.05.

Results: The patients' ages ranged from 22 to 78 years (mean: 48.5 years), with majority being females (90.4%) and of African descent (95.9%). Radiopaque CODs presented significantly higher rate of symptoms compared to radiolucent or mixed lesions (p = 0.02). The majority of incidental CODs were managed through observation (72%), while six incidental CODs underwent biopsy due to suspicion of more sinister lesions. Symptomatic lesions were mainly treated by curettage (29.7%) or local excision (48.6%), while only one symptomatic case was managed with observation and antibiotics (p = 0.0001).

Conclusion: Biopsy of asymptomatic COD should only be reserved for cases with inconclusive clinico-pathological features. The decision to surgically treat COD should be based on the presence of symptoms and infection. Early curettage or excision of infected COD is the most effective approach to eradicate the disease and prevent progression into osteomyelitis.

Clinical trial number: Not applicable.

目的:骨水泥-骨性发育不良(COD)是一种纤维-骨性病变,其治疗方法在文献中存在很大争议。由于缺乏对其管理的全面研究,本研究的目的是分析其管理并制定治疗方案。方法:对2005 ~ 2023年在两家三级转诊医院诊断为COD的124例患者进行多中心回顾性队列分析。对人口学、临床和放射学资料进行分析,并与治疗方法相关联。术后并发症如骨髓炎或病理性骨折随随访记录,以评估进一步治疗的需要。数据分析采用学生t检验和费雪精确检验。结果:患者年龄22 ~ 78岁,平均48.5岁,以女性(90.4%)和非洲裔(95.9%)居多。与放射透明或混合病变相比,不透明病变的症状发生率显著高于放射透明病变(p = 0.02)。大多数偶发性CODs(72%)通过观察处理,而6例偶发性CODs因怀疑有更险恶的病变而行活检。有症状的病变主要采用刮除(29.7%)或局部切除(48.6%)治疗,仅有1例有症状的患者采用观察和抗生素治疗(p = 0.0001)。结论:无症状COD的活检应仅用于临床病理特征不明确的病例。手术治疗COD的决定应基于症状和感染的存在。早期刮除或切除感染的COD是根除疾病和防止进展为骨髓炎的最有效方法。临床试验号:不适用。
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引用次数: 0
Evaluation of bone regeneration in rat calvaria using combination of enamel matrix derivate and bone graft substitute: a histological, histometric and immunohistochemical study. 牙釉质基质衍生物与骨移植替代物联合应用对大鼠颅骨骨再生的组织学、组织计量学和免疫组织化学研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-05 DOI: 10.1007/s10006-025-01390-y
Erik Neiva Ribeiro de Carvalho Reis, Germano de Lelis Bezerra Júnior, Leonardo de Freitas Silva, Tárik Ocon Braga Polo, Rayane Aquino de Amorim, Daniela Ponzoni, Roberta Okamoto, Rafael Scaf de Molon, Leonardo Perez Faverani, Idelmo Rangel Garcia Junior

Purpose: This study aimed to evaluate the bone repair process of standardized calvaria defects in rats treated with different bone substitute materials.

Methods: Critical size bone defects with 7 mm diameter were created in the right parietal bone of forty-eight rats using a trephine burr. The animals were randomly allocated to four different experimental groups according to the materials used to fill the defect, as follow: (1) Autogenous group: defects were filled with autogenous bone; (2) Bio-Oss group: defects were filled with demineralized bovine bone mineral; (3) EMD group: defects were filled with Emdogain®; and (4) EMD + Bone group: defects were filled with a combination of both Bone Ceramic® and Emdogain®. Euthanasia was performed after 30 and 60 days.

Results: Histometric analysis demonstrated for the 30-day period that all groups presented areas of bone neoformation, with the EMD + Bone group showing increased percentage of bone neoformation. For the 60-day period, there was a trend towards greater bone neoformation compared to the 30-day period, with a statistically significant difference between the EMD + Bone vs. Bio-Oss groups (p = 0.036). The percentage of new bone formation was significantly higher in the autogenous group compared to all the others. Moderate immunostaining of osteocalcin was observed in all groups at 30 days, which increased significantly in the 60-day period.

Conclusion: This study demonstrated suitable biological properties in the association of Emdogain® with Bone Ceramic®. However, further laboratory studies are needed to evaluate the osteoinductive properties of these materials, as well as their behavior in humans through clinical studies.

Clinical trial number: Not applicable.

目的:研究不同骨替代材料对大鼠标准化颅骨缺损的骨修复过程。方法:采用环钻法在48只大鼠右顶骨上形成直径为7mm的临界尺寸骨缺损。根据缺损填充材料的不同,将动物随机分为4个不同的实验组:(1)自体组:用自体骨填充缺损;(2) Bio-Oss组:用脱矿牛骨矿物质填充缺损;(3) EMD组:用Emdogain®填充缺损;(4) EMD + Bone组:用Bone Ceramic®和Emdogain®复合材料填充缺损。分别在30天和60天后进行安乐死。结果:组织计量学分析显示,在30天的时间内,所有组都出现骨新生区域,EMD + bone组骨新生百分比增加。在60天期间,与30天期间相比,有更大的骨新生趋势,EMD + bone组与Bio-Oss组之间的差异具有统计学意义(p = 0.036)。与所有其他组相比,自体组的新骨形成百分比明显更高。30 d时,各组骨钙素免疫染色均为中等水平,60 d时,骨钙素免疫染色显著升高。结论:本研究证明了Emdogain®与骨陶瓷®的相关生物学特性。然而,需要进一步的实验室研究来评估这些材料的骨诱导特性,以及通过临床研究来评估它们在人体中的行为。临床试验号:不适用。
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引用次数: 0
Treatment of Kasabach-Merritt syndrome in infants' maxillofacial regions with local, accurate administration of urea combined with methylprednisolone. 局部准确给药尿素联合甲基强的松龙治疗婴儿颌面部Kasabach-Merritt综合征
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-05-03 DOI: 10.1007/s10006-025-01393-9
Guangzhen Hu, Mengyin Cheng, Jing Huang, Changxian Dong

Background: Kasabach-Merritt syndrome (KMS) is a rear but dangerous type of hemangioma, which seriously threatens the life safety of KMS patients. The aim of this study is to explore the therapeutic and side effects of local administration of urea combined with methylprednisolone for the treatment of KMS in the maxillofacial region of infants.

Case presentation: A total of 14 cases of KMS in infants' maxillofacial region were treated with local injection of 40% urea solution and methylprednisone after the external carotid artery ligation. After 10-36 months of follow-up, 13 out of 14 cases were cured and 1 case was improved. Two cases relapsed and were effectively managed with additional urea injections over 6-10 days. Observed over a 1-2-month period post-treatment, external carotid artery catheterization with urea and methylprednisolone injection is effective for the treatment of maxillofacial KMS in infants.

Conclusion: The present study demonstrates that, external carotid artery ligation combined with urea and methylprednisolone can be curative for the treatment KMS in maxillofacial regions of infants, with little trauma and minimal side effect. The combined therapy is recommended for treating severe hemangiomas complicated by Kasabach-Merritt syndrome in maxillofacial region of infants.

背景:Kasabach-Merritt综合征(KMS)是一种少见但危险的血管瘤类型,严重威胁着KMS患者的生命安全。本研究的目的是探讨尿素联合甲基强的松龙局部给药治疗婴幼儿颌面KMS的疗效和副作用。病例介绍:采用颈外动脉结扎术后局部注射40%尿素溶液加甲基强的松治疗14例婴幼儿颌面KMS。随访10 ~ 36个月,治愈13例,好转1例。2例复发,经6-10天尿素注射有效治疗。在治疗后1-2个月的时间里,观察到尿素和甲基强的松龙注射的颈外动脉导管对治疗婴儿颌面KMS是有效的。结论:颈外动脉结扎联合尿素和甲基强的松龙治疗婴幼儿颌面部KMS可治愈,创伤小,副作用小。推荐联合治疗婴幼儿颌面部严重血管瘤合并卡萨巴赫-梅里特综合征。
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引用次数: 0
The juxtaoral organ of chievitz in publications about subgemmal neurogenous plaque is a misnomer: time to rename. 在关于鞘下神经性斑块的出版物中,下颌近端器官是一个用词不当:是时候重新命名了。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-04-30 DOI: 10.1007/s10006-025-01387-7
Fumio Ide, Shinnichi Sakamoto, Michiko Nishimura, Yuji Miyazaki, Kentaro Kikuchi
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引用次数: 0
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Oral and Maxillofacial Surgery-Heidelberg
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