Association of Thallium Exposure with Decreased Renal Function among Chinese Adults - China, 2017-2018.

IF 4.3 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 中国疾病预防控制中心周报 Pub Date : 2024-08-23 DOI:10.46234/ccdcw2024.186

Zheng Zhang, Miao Zhang, Yingli Qu, Feng Zhao, Saisai Ji, Zheng Li, Bing Wu, Chunxian Lyu, Haocan Song, Qi Sun, Yawei Li, Xu Zhang, Xulin Zheng, Yidan Qiu, Zihan Lu, Hui Fu, Lanjing Xu, Wenli Zhang, Yufei Luo, Fangyu Li, Jiayi Cai, Yuanduo Zhu, Ying Zhu, Zhaojin Cao, Yuebin Lyu, Xiaoming Shi

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Abstract

What is already known about this topic?: Thallium (Tl) is significantly more toxic than heavy metals such as lead, cadmium, and mercury. However, previous studies examining the relationship between Tl exposure and the risk of chronic kidney disease (CKD) have yielded inconsistent results.

What is added by this report?: The study demonstrated that elevated urinary Tl levels were associated with a higher prevalence of CKD and a reduced estimated glomerular filtration rate (eGFR), particularly among older adults. These findings were consistent in the restricted cubic spline (RCS) analyses.

What are the implications for public health practice?: This study identified Tl as a risk factor for decreased renal function, underscoring the need to enhance surveillance of Tl to mitigate the disease burden of CKD.

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铊暴露与中国成年人肾功能下降的关系 - 中国，2017-2018年。

本专题的已知信息：铊（Tl）的毒性明显高于铅、镉和汞等重金属。然而，以往对铊暴露与慢性肾病（CKD）风险之间关系的研究结果并不一致：该研究表明，尿液中钛含量的升高与慢性肾脏病发病率的升高和估计肾小球滤过率（eGFR）的降低有关，尤其是在老年人中。这些发现在限制性立方样条曲线（RCS）分析中是一致的：这项研究发现 Tl 是导致肾功能下降的一个风险因素，强调了加强 Tl 监测以减轻 CKD 疾病负担的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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中国疾病预防控制中心周报

CiteScore

5.90

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0.00%

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