Septal Perforation Quality of Life questionnaire (SEPEQOL): validation of a new instrument to assess patients undergoing endoscopic repair of a nasal septal perforation.

IF 2.4 2区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Head & Face Medicine Pub Date : 2024-09-02 DOI:10.1186/s13005-024-00451-z

Beatriz Arana-Fernández, Alfonso Santamaría-Gadea, Franklin Mariño-Sánchez, María Jesús Rojas-Lechuga, Isam Alobid

{"title":"Septal Perforation Quality of Life questionnaire (SEPEQOL): validation of a new instrument to assess patients undergoing endoscopic repair of a nasal septal perforation.","authors":"Beatriz Arana-Fernández, Alfonso Santamaría-Gadea, Franklin Mariño-Sánchez, María Jesús Rojas-Lechuga, Isam Alobid","doi":"10.1186/s13005-024-00451-z","DOIUrl":null,"url":null,"abstract":"Purpose: Nasoseptal perforations (NSP) are a clinically heterogeneous group of disorders with a wide range of available treatments. Patient-reported outcome measures (PROMs) can provide valuable insights for assessing clinical and surgical outcomes. This study aims to develop and validate a novel-specific questionnaire for patients with NSP.Methods: A multi-centre prospective observational study was conducted at two tertiary referral hospitals. \"Septal Perforation Quality of Life\" (SEPEQOL) was developed by a committee of experts. The psychometric properties, including reproducibility, reliability, validity, and responsiveness, were assessed.Results: The study included 96 symptomatic NSP patients and 30 healthy controls. SEPEQOL internal consistency was satisfactory [Cronbach´s α = 0.7843; 95% confidence interval (CI), 0.702-0.856]. Test-retest reliability was excellent, demonstrated by the absolute intraclass correlation (ICC = 0.974; 95% CI, 0.935-0.989, P-value < 0.001) and Bland-Altman plot (line bias = 1.6 ± 4.57; 95% CI -0.54-3.74, P-value < 0.001). The mean total SEPEQOL score was higher before surgery (25.16 ± 1.65) compared to 6-months after the procedure (13.72 ± 11.39), with a mean difference of 12.19 [standard deviation (SD) 10.76], P-value < 0.001.Conclusions: SEPEQOL is reliable, consistent, valid, and sensitive to change over time. SEPEQOL assesses the impact of health-related quality of life on NSP and its management in clinical practice. Moreover, it is easy to apply in clinical settings with minimal burden.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368029/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Head & Face Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13005-024-00451-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Nasoseptal perforations (NSP) are a clinically heterogeneous group of disorders with a wide range of available treatments. Patient-reported outcome measures (PROMs) can provide valuable insights for assessing clinical and surgical outcomes. This study aims to develop and validate a novel-specific questionnaire for patients with NSP.

Methods: A multi-centre prospective observational study was conducted at two tertiary referral hospitals. "Septal Perforation Quality of Life" (SEPEQOL) was developed by a committee of experts. The psychometric properties, including reproducibility, reliability, validity, and responsiveness, were assessed.

Results: The study included 96 symptomatic NSP patients and 30 healthy controls. SEPEQOL internal consistency was satisfactory [Cronbach´s α = 0.7843; 95% confidence interval (CI), 0.702-0.856]. Test-retest reliability was excellent, demonstrated by the absolute intraclass correlation (ICC = 0.974; 95% CI, 0.935-0.989, P-value < 0.001) and Bland-Altman plot (line bias = 1.6 ± 4.57; 95% CI -0.54-3.74, P-value < 0.001). The mean total SEPEQOL score was higher before surgery (25.16 ± 1.65) compared to 6-months after the procedure (13.72 ± 11.39), with a mean difference of 12.19 [standard deviation (SD) 10.76], P-value < 0.001.

Conclusions: SEPEQOL is reliable, consistent, valid, and sensitive to change over time. SEPEQOL assesses the impact of health-related quality of life on NSP and its management in clinical practice. Moreover, it is easy to apply in clinical settings with minimal burden.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

鼻中隔穿孔生活质量调查问卷（SEPEQOL）：验证用于评估鼻中隔穿孔内窥镜修复术患者的新工具。

目的：鼻中隔穿孔（NSP）是一种临床异质性疾病，有多种治疗方法可供选择。患者报告结果测量法（PROMs）可为评估临床和手术结果提供有价值的见解。本研究旨在开发并验证针对 NSP 患者的新型特异性问卷：在两家三级转诊医院开展了一项多中心前瞻性观察研究。由专家委员会编制了 "鼻中隔穿孔患者生活质量"（SEPEQOL）问卷。研究评估了该问卷的心理测量特性，包括再现性、可靠性、有效性和反应性：研究包括 96 名有症状的非典型肺炎患者和 30 名健康对照者。SEPEQOL 的内部一致性令人满意[Cronbach´s α = 0.7843；95% 置信区间 (CI)，0.702-0.856]。通过绝对类内相关性（ICC = 0.974；95% CI，0.935-0.989，P 值）可以看出，测试-重测可靠性极佳：SEPEQOL 可靠、一致、有效，对随时间发生的变化非常敏感。SEPEQOL 可评估健康相关生活质量对非典型肺炎及其临床治疗的影响。此外，它易于在临床环境中应用，负担极小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Head & Face Medicine DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.70

自引率

3.30%

发文量

审稿时长

>12 weeks

期刊介绍： Head & Face Medicine is a multidisciplinary open access journal that publishes basic and clinical research concerning all aspects of cranial, facial and oral conditions. The journal covers all aspects of cranial, facial and oral diseases and their management. It has been designed as a multidisciplinary journal for clinicians and researchers involved in the diagnostic and therapeutic aspects of diseases which affect the human head and face. The journal is wide-ranging, covering the development, aetiology, epidemiology and therapy of head and face diseases to the basic science that underlies these diseases. Management of head and face diseases includes all aspects of surgical and non-surgical treatments including psychopharmacological therapies.