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Depression in patients with chronic otolaryngology symptoms - A vicious cycle. 有慢性耳鼻喉科症状的患者抑郁--恶性循环。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-15 DOI: 10.1186/s13005-024-00464-8
Meera Niranjan Khadilkar, Keshava Pai K, Thripthi Rai, Vijendra Shenoy, Deviprasad Dosemane

Background: Depression is a common comorbidity among individuals with otolaryngologic disorders, particularly those with longstanding conditions. This study aims at analysing the sociodemographic profile of depressive disorders in patients with chronic otolaryngology symptoms or conditions, and the correlation with PHQ-9 score.

Methods: A cross-sectional study was conducted on a hundred patients presenting to the outpatient department with chronic otolaryngology symptoms or conditions. They were requested to fill in the PHQ-9 questionnaire, containing questions based on the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) for major depressive disorder (MDD).

Results: Median age was 39, male: female ratio was 1.17. Nasal obstruction (29%), ear discharge (25%), and headache (17%) were the common presenting complaints. Mean and median PHQ-9 scores were 5.03 and 4 respectively. Seven patients (7%) had MDD, while eleven (11%) had other depressive disorder; 9% of cases were found to have no significant otolaryngologic problem despite presenting with symptoms, two of which were found to have depressive disorder. Thirty-five (35%) and thirty-six (36%) patients had minimal and mild depressive symptoms respectively, while one (1%) had severe depressive symptoms. Statistical significance was noted for the duration of symptoms (p-value 0.005); high statistical significance was found for occupation and otolaryngology diagnosis (p-value < 0.001 each). PHQ-9 score showed statistical significance in comparison with gender and duration of symptoms (p-value 0.046 and 0.005 respectively). Correlation of severity of depressive disorder revealed statistical significance with gender (p-value 0.049) and high statistical significance with duration of symptoms (p-value < 0.001).

Conclusion: Chronic otolaryngology conditions are associated with significant morbidity, attributable to longstanding disturbing symptoms and prolonged treatment protocols, leading to depression. Nevertheless, depression in chronic otolaryngology disorders may aggravate or overlap the clinical symptoms or may go undetected. Hence it may be worthwhile to evaluate for depressive disorders in chronic patients presenting to otolaryngology.

背景:抑郁症是耳鼻咽喉科疾病患者,尤其是长期患病者的常见并发症。本研究旨在分析慢性耳鼻喉症状或病症患者抑郁障碍的社会人口学特征,以及与 PHQ-9 评分的相关性:方法:我们对 100 名因慢性耳鼻喉症状或病症到门诊部就诊的患者进行了横断面研究。要求他们填写 PHQ-9 问卷,其中的问题以第四版《精神疾病诊断与统计手册》(DSM-IV)中的重度抑郁障碍(MDD)为基础:中位年龄为 39 岁,男女比例为 1.17。鼻塞(29%)、耳流脓(25%)和头痛(17%)是常见的主诉。PHQ-9评分的平均值和中位数分别为5.03分和4分。7名患者(7%)患有多发性抑郁症,11名患者(11%)患有其他抑郁症;9%的病例尽管有症状,但没有明显的耳鼻喉问题,其中2名患者患有抑郁症。35%和36%的患者分别有轻微和轻度抑郁症状,1%的患者有严重抑郁症状。症状持续时间具有统计学意义(p 值为 0.005);职业和耳鼻喉科诊断具有高度统计学意义(p 值为 0.005):慢性耳鼻喉科疾病的发病率很高,这是因为长期的症状困扰和治疗方案的延长导致了抑郁症。然而,慢性耳鼻喉科疾病中的抑郁症可能会加重或重叠临床症状,也可能未被发现。因此,值得对耳鼻喉科慢性病患者进行抑郁障碍评估。
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引用次数: 0
Evaluating sagittal condylar inclination: a comparative analysis of various digital workflow measures. 评估矢状髁状突倾斜度:各种数字工作流程测量方法的比较分析。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-15 DOI: 10.1186/s13005-024-00471-9
Yeqing Wang, Xin Wang, Litong Li, Meng Cao

Introduction: This study aims to compare sagittal condylar inclination (SCI) measurements derived from three workflows: intraoral scan (IOS) aligned with cone-beam computed tomography (CBCT), IOS aligned with facial scan (FS), and a jaw motion analyzer (JMA) system, in a cohort of young individuals with established normal occlusion. Additionally, the study aims to identify sources contributing to variance in these measurement approaches.

Methods: Twenty-four healthy individuals exhibiting normal occlusion were enrolled in this clinical trial. The SCI was delineated using a virtual articulator (VA) by aligning IOS with both CBCT and FS, creating two distinct workflows labeled CBCT-IOS and FS-IOS, respectively. Concurrently, SCI measurements were also acquired using a JMA. The normality of data distribution for the difference in bilateral SCI measurements within each workflow was tested using the Shapiro-Wilk test. Depending on the outcomes of this test, we utilized either a paired-sample T-test or Wilcoxon test for bilateral SCI comparisons. The inter-workflow differences were assessed using the Kruskal-Wallis H test. Bland-Altman plots were assess the interchangeability and consistency across each pair of digital methods and to evaluate the aggregate consistency among the trio of digital approaches.

Results: The analysis revealed that the CBCT-IOS workflow yielded the lowest average SCI measurements, whereas the JMA workflow produced the highest values. No significant differences were found in the SCI measurements between the left and right sides obtained by CBCT-IOS and JMA (P > .05), with the exception of the FS-IOS workflow (P = .002). Additionally, inter-flow comparisons revealed no significant differences in SCI measurements (P > .05), except when contrasting the SCI as measured by CBCT-IOS and JMA (P = .0131). The Bland-Altman plots demonstrated a high degree of consistency and 95% limits of agreement across the three digital workflows.

Conclusion: SCI measurements obtained from the three digital workflows exhibit a high degree of consistency and are interchangeable, affirming their clinical applicability for precise SCI assessment in young individuals with normal occlusion.

简介:本研究旨在比较三种工作流程得出的矢状髁状突倾角(SCI)测量结果:与锥束计算机断层扫描(CBCT)对齐的口内扫描(IOS)、与面部扫描(FS)对齐的口内扫描(IOS)以及颌骨运动分析仪(JMA)系统。此外,该研究还旨在找出造成这些测量方法差异的原因:24名咬合正常的健康人参加了此次临床试验。通过将 IOS 与 CBCT 和 FS 对齐,使用虚拟关节器(VA)划定 SCI,创建两个不同的工作流程,分别标记为 CBCT-IOS 和 FS-IOS。同时,还使用 JMA 采集了 SCI 测量数据。使用 Shapiro-Wilk 检验法检验了每个工作流程中双侧 SCI 测量值差异的数据分布的正态性。根据检验结果,我们采用配对样本 T 检验或 Wilcoxon 检验进行双侧 SCI 比较。工作流程间的差异采用 Kruskal-Wallis H 检验进行评估。布兰德-阿尔特曼图评估了每对数字方法之间的互换性和一致性,并评估了三种数字方法之间的总体一致性:分析结果显示,CBCT-IOS 工作流程得出的 SCI 平均测量值最低,而 JMA 工作流程得出的数值最高。通过 CBCT-IOS 和 JMA 获得的左右侧 SCI 测量值没有发现明显差异(P > .05),但 FS-IOS 工作流程除外(P = .002)。此外,流程间比较显示 SCI 测量值无明显差异(P > .05),但 CBCT-IOS 和 JMA 测量的 SCI 值对比除外(P = .0131)。布兰-阿尔特曼图显示了三种数字工作流程的高度一致性和 95% 的一致性限值:结论:通过三种数字工作流程获得的 SCI 测量值具有高度一致性和互换性,这肯定了它们在临床上适用于对闭塞正常的年轻人进行精确的 SCI 评估。
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Head & Face Medicine
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