Virucidal activity of chlorine dioxide in combination with acetic acid or citric acid and a surfactant, in presence of interfering substances, against polio-, adeno- and murine norovirus in suspension-, carrier- and four-field tests.
Patryk Tarka, Arkadiusz Chruściel, Wiesław Hreczuch, Krzysztof Kanecki, Aneta Nitsch-Osuch
{"title":"Virucidal activity of chlorine dioxide in combination with acetic acid or citric acid and a surfactant, in presence of interfering substances, against polio-, adeno- and murine norovirus in suspension-, carrier- and four-field tests.","authors":"Patryk Tarka, Arkadiusz Chruściel, Wiesław Hreczuch, Krzysztof Kanecki, Aneta Nitsch-Osuch","doi":"10.3205/dgkh000492","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to investigate whether the virucidal effectiveness of chlorine dioxid against adenovirus and murine norovirus can be improved by combining it with carboxylic acids and surfactants.</p><p><strong>Method: </strong>The virucidal efficacy against polio-, adeno- and murine norovirus has been tested in presence of interfering substances in the quantitative suspension test according to EN 14476, the carrier test without mechanical action according to EN 16777, and in the four-field test according to EN 16615.Three chlorine-dioxide-based surface disinfectants were tested: a two-component cleaning disinfectant concentrate for large surfaces, a ready-to-use (RTU) foam, and an RTU gel.</p><p><strong>Results: </strong>Cleaning and disinfecting preparations based on chlorine dioxide, applied at various concentrations, in combination with acetic acid or citric acid and surfactants, are virucidally active against polio-, adeno-, and norovirus after an exposure time of 5 minutes in presence of interfering substances.</p>","PeriodicalId":12738,"journal":{"name":"GMS Hygiene and Infection Control","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367254/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"GMS Hygiene and Infection Control","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3205/dgkh000492","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: The aim of the study was to investigate whether the virucidal effectiveness of chlorine dioxid against adenovirus and murine norovirus can be improved by combining it with carboxylic acids and surfactants.
Method: The virucidal efficacy against polio-, adeno- and murine norovirus has been tested in presence of interfering substances in the quantitative suspension test according to EN 14476, the carrier test without mechanical action according to EN 16777, and in the four-field test according to EN 16615.Three chlorine-dioxide-based surface disinfectants were tested: a two-component cleaning disinfectant concentrate for large surfaces, a ready-to-use (RTU) foam, and an RTU gel.
Results: Cleaning and disinfecting preparations based on chlorine dioxide, applied at various concentrations, in combination with acetic acid or citric acid and surfactants, are virucidally active against polio-, adeno-, and norovirus after an exposure time of 5 minutes in presence of interfering substances.
引言研究的目的是探讨二氧氯是否可以通过与羧酸和表面活性剂结合来提高对腺病毒和小鼠诺如病毒的杀毒效果:在有干扰物质存在的情况下,根据 EN 14476 标准进行了定量悬浮试验,根据 EN 16777 标准进行了无机械作用载体试验,根据 EN 16615 标准进行了四场试验,对脊髓灰质炎病毒、腺病毒和小鼠诺如病毒的杀病毒效果进行了测试:结果:在有干扰物质存在的情况下,以不同浓度的二氧化氯为基础的清洁和消毒制剂与醋酸或柠檬酸和表面活性剂混合使用,在暴露 5 分钟后对脊髓灰质炎病毒、腺病毒和诺如病毒具有杀毒活性。