Unmet Medication Needs and the Association with Mortality in Older Adults: Equality-Oriented Monitoring toward Universal Health Coverage.

IF 7 2区 医学 Q1 GERIATRICS & GERONTOLOGY Aging and Disease Pub Date : 2024-08-09 DOI:10.14336/AD.2024.0626
Minmin Wang, Yikai Feng, Yanan Luo, Yinzi Jin, Minghui Ren, Zhi-Jie Zheng
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Abstract

With population aging becoming a global trend, the unmet medication needs of older individuals are steadily increasing, potentially leading to a decline in quality of life and increased mortality. To identify unmet medication needs and inequality, and the association with health outcomes. A total of 69,443 participants in 31 countries from five international cohorts of aging were included. We measured the unmet medication needs level across sociodemographic strata. We developed an equality-oriented health care service coverage index (ESCI) and explored its relation to all-cause mortality in older adults over 55 years of age. Unmet medication needs in older adults with chronic conditions reached 41.84%. The highest unmet needs were observed in older age groups and participants with multimorbidity. The ESCI was further constructed by covering both the unmet needs level and inequality. An inverse association was observed between the ESCI and all-cause mortality in older adults (β=-16.81, P=0.047) as well as mortality rate owing to noncommunicable diseases (β=-17.58, P=0.041). The ESCI was inversely associated with mortality in older adults. This index could serve as a process evaluation indicator in assessing the progress toward UHC and healthy aging.

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未满足的用药需求及其与老年人死亡率的关系:以平等为导向的全民医保监测。
随着人口老龄化成为全球趋势,老年人未得到满足的用药需求正在稳步增加,这可能会导致生活质量下降和死亡率上升。为了确定未满足的用药需求和不平等现象,以及与健康结果的关联。我们共纳入了来自 31 个国家的 69443 名参与者,他们来自五个国际老龄化队列。我们测量了不同社会人口阶层中未满足的用药需求水平。我们制定了以平等为导向的医疗保健服务覆盖指数(ESCI),并探讨了该指数与 55 岁以上老年人全因死亡率的关系。患有慢性疾病的老年人未满足的药物需求达到 41.84%。据观察,未满足需求最高的是老年群体和患有多病的参与者。通过对未满足需求水平和不平等情况的分析,进一步构建了 ESCI。观察发现,ESCI 与老年人全因死亡率(β=-16.81,P=0.047)以及非传染性疾病死亡率(β=-17.58,P=0.041)之间存在反向关联。ESCI与老年人死亡率成反比。该指数可作为评估全民医保和健康老龄化进展的过程评价指标。
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来源期刊
Aging and Disease
Aging and Disease GERIATRICS & GERONTOLOGY-
CiteScore
14.60
自引率
2.70%
发文量
138
审稿时长
10 weeks
期刊介绍: Aging & Disease (A&D) is an open-access online journal dedicated to publishing groundbreaking research on the biology of aging, the pathophysiology of age-related diseases, and innovative therapies for conditions affecting the elderly. The scope encompasses various diseases such as Stroke, Alzheimer's disease, Parkinson’s disease, Epilepsy, Dementia, Depression, Cardiovascular Disease, Cancer, Arthritis, Cataract, Osteoporosis, Diabetes, and Hypertension. The journal welcomes studies involving animal models as well as human tissues or cells.
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