Environmental Risk Factors for Visceral Leishmaniasis: An Analysis of Housing Types and Behavioral Factors in Baringo County, Kenya.

Abstract

Visceral leishmaniasis (VL) is endemic in Baringo County, Kenya, and contributes significantly to the burden of disease in the region. Housing structures and other environmental risk factors contribute to transmission dynamics, but these have not been specifically studied in Baringo. The aim of this study was to increase understanding of VL transmission in the region through determining relationships between VL infection, housing, and other environmental factors. Data collection occurred from February 1 to May 31, 2023 at Chemolingot Sub-County Hospital and patients' homesteads via questionnaires of primary VL patients being treated and VL follow-up patients who were still residing in the same house as when the infection occurred. Factors assessed were housing structures, proximity to vector breeding and resting sites, and prevention and control measure practices. A baseline assessment of housing types was conducted through direct ethnographic observation and used in the analysis. Forty-one patients were included in the study. A χ2 analysis and Fisher's test were used to determine association between VL infection and housing materials, where VL patient housing data were compared with the regional baseline assessment. Significant associations with VL infection were found between mud and stick walls (P <0.001); mud walls (P <0.001); mud, stick, and grass combination walls (P = 0.02); and stick and grass walls (P <0.001). Behavior comparison showed that most VL-protective behaviors were practiced by follow-up patients after infection. Results showed an increased need for VL prevention focusing on environmental factors.