Low Rate of AVN and Complications in Unstable SCFE With Epiphyseal-metaphyseal Discontinuity After Treatment With a Modified Dunn Procedure.

IF 4.2 2区 医学 Q1 ORTHOPEDICS Clinical Orthopaedics and Related Research® Pub Date : 2024-09-01 Epub Date: 2024-05-14 DOI:10.1097/CORR.0000000000003123
Kai Ziebarth, Till D Lerch, Tilman Kaim, Joseph M Schwab, Simon D Steppacher, Moritz Tannast, Klaus A Siebenrock
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In addition, since the Loder classification of unstable is reportedly different than actual intraoperatively observed instability (that is, discontinuity between the femoral head epiphysis and proximal femoral metaphysis), the overall risk of developing AVN, as well as the potential complications of treatment of these patients with the modified Dunn procedure, are unknown.</p><p><strong>Questions/purposes: </strong>To evaluate the modified Dunn procedure for the treatment of patients with epiphyseal-metaphyseal discontinuity, we asked: (1) What was the survivorship free from AVN at 10 years? (2) What was the survivorship free from subsequent surgery and/or complications at 10 years? (3) What were the clinical and patient-reported outcome scores?</p><p><strong>Methods: </strong>In a retrospective analysis, we identified 159 patients (159 hips) treated with a modified Dunn procedure for SCFE between 1998 and 2020, of whom 97% (155 of 159) had documentation about intraoperatively observed epiphyseal-metaphyseal stability. Of those, 37% (58 of 155) of patients were documented to have intraoperatively observed epiphyseal-metaphyseal discontinuity and were considered eligible for inclusion, whereas 63% (97 of 155) had documented epiphyseal-metaphyseal stability and were excluded. No patients were lost to follow-up before the 2-year minimum. All patients were assessed for survival, but 7% (4 of 58) did not fill out our outcomes score questionnaire. This resulted in 93% (54 of 58) of patients who were available for outcome score assessment. Additionally, 50% (29 of 58) of patients had not been seen within the last 5 years; they are included, but we note that there is uncertainty about their status. The median (range) age at surgery was 13 years (10 to 16), and the sex ratio was 60% (35 of 58) male and 40% (23 of 58) female patients. Sixty-four percent (37 of 58) of patients were classified as acute-on-chronic, and 17% (10 of 58) of patients were classified as acute. Forty-seven percent (27 of 58) of patients presented with severe slips and 43% (25 of 58) of patients with moderate slips based on radiographic classification. All patients underwent surgical hip dislocation with the modified Dunn procedure to correct the slip deformity and provide stabilization. Complications and reoperations were assessed from a review of electronic medical records, and a Kaplan-Meier estimator was used to estimate survivorship free from complications and reoperations at 10 years. Clinical examination results and questionnaire responses were evaluated at minimum 2-year follow-up.</p><p><strong>Results: </strong>Kaplan-Meier survivorship free from AVN was 93% (95% CI 87% to 100%) at 10 years. Survivorship free from any reoperation was 75% (95% CI 64% to 88%) at 10 years. In addition, survivorship free from complications, defined as development of AVN, reoperation, or a Sink Grade II complication or higher, was 57% (95% CI 45% to 73%) at 10 years. The median (range) Merle D'Aubigne Postel score was 18 (14 to 18) for the patients who did not develop AVN, and 12 (6 to 16) for the four patients who developed AVN (p < 0.001). The median modified Harris hip score was 100 (74 to 100) in the non-AVN cohort and 65 (37 to 82) in the AVN cohort (p = 0.001). 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引用次数: 0

Abstract

Background: The risk of developing avascular necrosis (AVN) in the setting of an unstable slipped capital femoral epiphysis (SCFE) that is undergoing treatment with the modified Dunn procedure is not well understood. In addition, since the Loder classification of unstable is reportedly different than actual intraoperatively observed instability (that is, discontinuity between the femoral head epiphysis and proximal femoral metaphysis), the overall risk of developing AVN, as well as the potential complications of treatment of these patients with the modified Dunn procedure, are unknown.

Questions/purposes: To evaluate the modified Dunn procedure for the treatment of patients with epiphyseal-metaphyseal discontinuity, we asked: (1) What was the survivorship free from AVN at 10 years? (2) What was the survivorship free from subsequent surgery and/or complications at 10 years? (3) What were the clinical and patient-reported outcome scores?

Methods: In a retrospective analysis, we identified 159 patients (159 hips) treated with a modified Dunn procedure for SCFE between 1998 and 2020, of whom 97% (155 of 159) had documentation about intraoperatively observed epiphyseal-metaphyseal stability. Of those, 37% (58 of 155) of patients were documented to have intraoperatively observed epiphyseal-metaphyseal discontinuity and were considered eligible for inclusion, whereas 63% (97 of 155) had documented epiphyseal-metaphyseal stability and were excluded. No patients were lost to follow-up before the 2-year minimum. All patients were assessed for survival, but 7% (4 of 58) did not fill out our outcomes score questionnaire. This resulted in 93% (54 of 58) of patients who were available for outcome score assessment. Additionally, 50% (29 of 58) of patients had not been seen within the last 5 years; they are included, but we note that there is uncertainty about their status. The median (range) age at surgery was 13 years (10 to 16), and the sex ratio was 60% (35 of 58) male and 40% (23 of 58) female patients. Sixty-four percent (37 of 58) of patients were classified as acute-on-chronic, and 17% (10 of 58) of patients were classified as acute. Forty-seven percent (27 of 58) of patients presented with severe slips and 43% (25 of 58) of patients with moderate slips based on radiographic classification. All patients underwent surgical hip dislocation with the modified Dunn procedure to correct the slip deformity and provide stabilization. Complications and reoperations were assessed from a review of electronic medical records, and a Kaplan-Meier estimator was used to estimate survivorship free from complications and reoperations at 10 years. Clinical examination results and questionnaire responses were evaluated at minimum 2-year follow-up.

Results: Kaplan-Meier survivorship free from AVN was 93% (95% CI 87% to 100%) at 10 years. Survivorship free from any reoperation was 75% (95% CI 64% to 88%) at 10 years. In addition, survivorship free from complications, defined as development of AVN, reoperation, or a Sink Grade II complication or higher, was 57% (95% CI 45% to 73%) at 10 years. The median (range) Merle D'Aubigne Postel score was 18 (14 to 18) for the patients who did not develop AVN, and 12 (6 to 16) for the four patients who developed AVN (p < 0.001). The median modified Harris hip score was 100 (74 to 100) in the non-AVN cohort and 65 (37 to 82) in the AVN cohort (p = 0.001). Median HOOS total score was 95 (50 to 100) in the non-AVN cohort and 53 (40 to 82) in the AVN cohort (p = 0.002).

Conclusion: Although the modified Dunn procedure is technically challenging, this study shows that in experienced hands, patients with who have demonstrated epiphyseal-metaphyseal discontinuity can be treated with a low risk of AVN and subsequent surgery. Referral of these patients to specialists who have substantial expertise in this procedure is recommended to improve patient outcomes. Prospective, long-term observational studies will help us identify these high-risk patients preoperatively and determine the long-term success of this procedure.

Level of evidence: Level IV, therapeutic study.

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采用改良邓恩手术治疗不稳定的 SCFE 伴有骺端-金属骺端不连续的患者,其 AVN 和并发症发生率较低。
背景:目前还不太清楚正在接受改良邓恩手术治疗的不稳定股骨头骺滑脱(SCFE)患者发生血管坏死(AVN)的风险。此外,据报道,由于 Loder 对不稳定的分类与术中观察到的实际不稳定(即股骨头骨骺和股骨近端骨骺之间不连续)不同,因此这些患者在接受改良 Dunn 手术治疗时,发生 AVN 的总体风险以及潜在并发症尚不清楚:为了评估改良邓恩手术对骺端-骺端不连续患者的治疗效果,我们提出了以下问题:(1)10 年后无 AVN 的存活率是多少?(2)10 年后无后续手术和/或并发症的存活率如何?(3)临床和患者报告的结果评分如何?在一项回顾性分析中,我们确定了1998年至2020年间接受改良Dunn术治疗的159例SCFE患者(159髋),其中97%(159例中的155例)有术中观察到的骺板-骺端稳定性的记录。其中,37%的患者(155 例中的 58 例)记录有术中观察到的骺端-骺端不连续,符合纳入条件,而 63%的患者(155 例中的 97 例)记录有骺端-骺端稳定性,被排除在外。没有患者在最短 2 年随访期之前失去随访机会。所有患者都进行了存活评估,但有 7%(58 人中有 4 人)没有填写我们的结果评分问卷。因此,93% 的患者(58 例中的 54 例)可以接受结果评分评估。此外,有 50%(58 例中的 29 例)的患者在过去 5 年中未曾就诊;这些患者也包括在内,但我们注意到他们的状况并不确定。手术时的年龄中位数(范围)为 13 岁(10 到 16 岁),性别比例为 60%(58 人中有 35 名男性)和 40%(58 人中有 23 名女性)。64%的患者(58 例中的 37 例)被归类为急性-慢性,17%的患者(58 例中的 10 例)被归类为急性。根据放射学分类,47%的患者(58 例中的 27 例)为重度滑脱,43%的患者(58 例中的 25 例)为中度滑脱。所有患者都接受了髋关节脱位手术,采用改良邓恩手术矫正滑脱畸形并提供稳定。并发症和再手术情况通过查阅电子病历进行评估,并使用卡普兰-梅耶估计器估算10年后无并发症和再手术的存活率。在至少两年的随访中对临床检查结果和问卷答复进行评估:10 年后,无 AVN 的 Kaplan-Meier 存活率为 93%(95% CI 为 87% 至 100%)。10年后,无任何再次手术的存活率为75%(95% CI为64%至88%)。此外,10 年后无并发症(定义为出现 AVN、再次手术或 Sink II 级或以上并发症)的存活率为 57%(95% CI 为 45% 至 73%)。未发生 AVN 的患者的 Merle D'Aubigne Postel 评分中位数(范围)为 18(14 至 18),发生 AVN 的四名患者的 Merle D'Aubigne Postel 评分中位数(范围)为 12(6 至 16)(P < 0.001)。非 AVN 患者的改良哈里斯髋关节评分中位数为 100(74 至 100),而 AVN 患者的改良哈里斯髋关节评分中位数为 65(37 至 82)(P = 0.001)。非 AVN 队列的 HOOS 总分中位数为 95(50 至 100),AVN 队列的 HOOS 总分中位数为 53(40 至 82)(P = 0.002):结论:虽然改良邓恩手术在技术上具有挑战性,但本研究表明,在经验丰富的医生手中,已显示出骺端-骺端不连续的患者可以接受治疗,且发生 AVN 和后续手术的风险较低。建议将这些患者转诊给在该手术方面拥有丰富专业知识的专科医生,以改善患者的治疗效果。前瞻性的长期观察研究将有助于我们在术前识别这些高风险患者,并确定该手术的长期成功率:证据级别:IV级,治疗性研究。
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来源期刊
CiteScore
7.00
自引率
11.90%
发文量
722
审稿时长
2.5 months
期刊介绍: Clinical Orthopaedics and Related Research® is a leading peer-reviewed journal devoted to the dissemination of new and important orthopaedic knowledge. CORR® brings readers the latest clinical and basic research, along with columns, commentaries, and interviews with authors.
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