Identification of the novel HLA-B*49:01:01:22 allele in an Indian renal transplant donor by next generation sequencing

IF 5.9 4区 医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-09-03 DOI:10.1111/tan.15665
Ram Mohan Jaiswal, Shyam Swaroop, Ashina Singla, Shweta Sharma, Suraj Godara
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引用次数: 0

Abstract

HLA-B*49:01:01:22 differs from HLA-B*49:01:01:01 by a single nucleotide C->G change in intron 5 at gDNA 2451.

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通过新一代测序鉴定印度肾移植供体中的新型 HLA-B*49:01:01:22 等位基因。
HLA-B*49:01:01:22与HLA-B*49:01:01:01的不同之处在于gDNA 2451的内含子5中的单核苷酸C->G变化。
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来源期刊
HLA
HLA Immunology and Microbiology-Immunology
CiteScore
3.00
自引率
28.80%
发文量
368
期刊介绍: HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
期刊最新文献
A novel HLA-C*07 variant allele, HLA-C*07:01:01:141, identified by next-generation sequencing Identification of the novel HLA-B*56:100 allele by next-generation sequencing The novel HLA-A*24:393 allele, identified by Sanger dideoxy nucleotide sequencing in a Taiwanese individual Discovery of the novel HLA-B*35:611 allele, a variant of the HLA-B*35:64:01 allele Discovery of potential recombinant alleles HLA-DRB3*02:171 and HLA-DRB5*01:140
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