Circovirus Hepatitis in Immunocompromised Patient, Switzerland

IF 7.2 2区 医学 Q1 IMMUNOLOGY Emerging Infectious Diseases Pub Date : 2024-09-03 DOI:10.3201/eid3010.240678
Baptiste Hamelin, Philippe Pérot, Ian Pichler, Jasmin D. Haslbauer, David Hardy, David Hing, Sarra Loulizi, Béatrice Regnault, Anouk Pieters, Ingmar Heijnen, Caroline Berkemeier, Maria Mancuso, Verena Kufner, Niels Willi, Anne Jamet, Nolwenn Dheilly, Marc Eloit, Mike Recher, Michael Huber, Kirsten D. Mertz
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Abstract

We identified a novel human circovirus in an immunocompromised 66-year-old woman with sudden onset of self-limiting hepatitis. We detected human circovirus 1 (HCirV-1) transcripts in hepatocytes and the HCirV-1 genome long-term in the patient’s blood, stool, and urine. HCirV-1 is an emerging human pathogen that persists in susceptible patients.

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免疫力低下患者的圆环病毒肝炎,瑞士
我们在一名突发自限性肝炎、免疫力低下的 66 岁女性患者身上发现了一种新型人类圆环病毒。我们在肝细胞中检测到了人类圆环病毒 1(HCirV-1)转录本,并在患者的血液、粪便和尿液中长期检测到了 HCirV-1 基因组。HCirV-1 是一种新出现的人类病原体,会在易感患者体内持续存在。
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来源期刊
Emerging Infectious Diseases
Emerging Infectious Diseases 医学-传染病学
CiteScore
17.30
自引率
1.70%
发文量
505
审稿时长
1 months
期刊介绍: Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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