A review on the effect of soy bioactive components on growth and health outcomes in pigs and broiler chickens.

Abstract

While soy products have long been included in animal diets for their macronutrient fractions, more recent work has focused on the immunomodulatory potential of bioactive components of this feedstuff. This comprehensive review aims to identify the current state of knowledge on minor soy fractions and their impact on the health and growth of pigs and broiler chickens to better direct future research. A total of 7,683 publications were screened, yet only 151 were included in the review after exclusion criteria were applied, with the majority (n = 87) of these studies conducted in pigs. In both species, antinutritional factors and carbohydrates, like stachyose and raffinose, were the most frequently studied categories of bioactive components. For both categories, most publications were evaluating ways to decrease the prevalence of the examined components in soy products, especially when fed at earlier ages. Overall, most studies evaluated the effect of the bioactive component on performance-related outcomes (n = 137), followed by microbial analysis (n = 38) and intestinal structure and integrity measures (n = 37). As they were analyzed in the majority of publications, antinutritional factors were also the most frequently investigated category in relation to each specific outcome. This trend did not hold true for microbiota- or antioxidant-associated outcomes, which were most often studied with carbohydrates or polyphenols, respectively. Changes to the host microbiota have the potential to modulate the immune system, feed intake, and social behaviors through the microbiota-gut-brain axis, though few publications measured behavior and brain characteristics as an outcome. Other identified gaps in research included the study of soy saponins, as most research focused on saponins derived from other plants, the study of phytosterols outside of their role in cardiovascular or reproductive outcomes, and the general examination of bioactive peptides. Overall, given soy's popularity as a current constituent of animal feed, additional research into these bioactive components may serve to define the value of soy products through their potential ability to support the productivity, health, and well-being of animals.