The increasing prevalence of cancer in the elderly: An investigation of epidemiological trends

IF 2.2 Q3 GERIATRICS & GERONTOLOGY Aging Medicine Pub Date : 2024-08-18 DOI:10.1002/agm2.12347
Ramya Prathap, Sherlin Kirubha, Aravindhan Thiyaga Rajan, Santhosh Manoharan, Karthikeyan Elumalai
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Abstract

Cancer poses a significant health threat to the elderly, accounting for a substantial proportion of cancer patients aged 65 and above. As life expectancy continues to rise and the population ages, the incidence of cancer in the elderly is expected to increase further. Age is a major risk factor for the majority of common cancers, with the incidence and prevalence rising as individuals grow older. Factors such as chemoprevention and environmental carcinogen elimination may influence the process of carcinogenesis. Studies reveal that the incidence and mortality rates of various cancers in the elderly and extremely old individuals are on the rise worldwide, with most types peaking around the age of 75 to 90, followed by a sharp decline. Birth cohort and period effects also play a complex role in the connection between aging and cancer risk. Clinical trials often exclude older individuals, limiting our understanding of cancer treatments' effects on this particular age group. More research is needed to focus on the unique requirements of older adults with cancer.

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老年人癌症发病率不断上升:流行病学趋势调查。
癌症对老年人的健康构成重大威胁,在 65 岁及以上的癌症患者中占很大比例。随着预期寿命的不断延长和人口的老龄化,预计老年人的癌症发病率将进一步上升。年龄是大多数常见癌症的主要风险因素,随着年龄的增长,癌症的发病率和流行率也在上升。化学预防和消除环境致癌物等因素可能会影响致癌过程。研究显示,全球老年人和高龄老人的各种癌症发病率和死亡率呈上升趋势,大多数类型的癌症在 75 至 90 岁左右达到峰值,随后急剧下降。出生组群和时期效应在老龄化与癌症风险之间也起着复杂的作用。临床试验通常将老年人排除在外,这限制了我们对癌症治疗对这一特殊年龄组的影响的了解。我们需要开展更多的研究来关注老年癌症患者的独特需求。
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来源期刊
Aging Medicine
Aging Medicine Medicine-Geriatrics and Gerontology
CiteScore
4.10
自引率
0.00%
发文量
38
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