Self-Reported Effect of Mikania laevigata Syrup in Treating Acute Cough in Adults and Children: Preliminary Evidence From an Uncontrolled, Observational Study
F. Carmona , L. Chaves , E.C. Moreira , G.R. Ramos , I.M.C. Dandaro , J.S. Coppede , A.M.S. Pereira
{"title":"Self-Reported Effect of Mikania laevigata Syrup in Treating Acute Cough in Adults and Children: Preliminary Evidence From an Uncontrolled, Observational Study","authors":"F. Carmona , L. Chaves , E.C. Moreira , G.R. Ramos , I.M.C. Dandaro , J.S. Coppede , A.M.S. Pereira","doi":"10.1016/j.hermed.2024.100929","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p><em>Mikania laevigata</em> Sch. Bip. ex Baker (<em>Asteraceae</em>), popularly known as ‘guaco,’ is a medicinal plant widely used to treat cough in Brazil and South America. Although it is marketed with this indication, no clinical evidence supports its effectiveness in treating cough. This study aimed to assess the self-reported effect of a <em>M laevigata</em> syrup in treating acute cough in adults and children.</p></div><div><h3>Methods</h3><p>An online/telephone-based survey was conducted in 1 309 adult and paediatric patients who received <em>M laevigata</em> syrup for acute cough in Jardinópolis (São Paulo, Brazil) in 2021 and 2022. Seventy-six responses were received (5.8% of those eligible). The frequency, intensity, and impact of coughing on sleep were assessed using a numeric scale (0–10 points) and compared before and after treatment using a paired non-parametric test.</p></div><div><h3>Results</h3><p>The participants used <em>M laevigata</em> syrup primarily for COVID-19 and discomfort caused by coughing. They reported intense frequency (median 8 [range 3, 10]), intensity (10 [2, 10]), and impact of coughing on sleep (10 [0, 10]) before treatment, and significant improvements in these three characteristics after treatment (<em>P</em> < 0.001 for all comparisons). They also reported a quick onset effect (11%), but a few patients complained about a taste that was too sweet or unpalatable (7%).</p></div><div><h3>Conclusions</h3><p>Adults and children using <em>M laevigata</em> syrup reported significant improvements in frequency, intensity, and impact of coughing on sleep. Besides, these patients highlighted the quick effect onset and the excellent tolerability.</p></div>","PeriodicalId":56077,"journal":{"name":"Journal of Herbal Medicine","volume":"47 ","pages":"Article 100929"},"PeriodicalIF":2.2000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Herbal Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210803324000861","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Mikania laevigata Sch. Bip. ex Baker (Asteraceae), popularly known as ‘guaco,’ is a medicinal plant widely used to treat cough in Brazil and South America. Although it is marketed with this indication, no clinical evidence supports its effectiveness in treating cough. This study aimed to assess the self-reported effect of a M laevigata syrup in treating acute cough in adults and children.
Methods
An online/telephone-based survey was conducted in 1 309 adult and paediatric patients who received M laevigata syrup for acute cough in Jardinópolis (São Paulo, Brazil) in 2021 and 2022. Seventy-six responses were received (5.8% of those eligible). The frequency, intensity, and impact of coughing on sleep were assessed using a numeric scale (0–10 points) and compared before and after treatment using a paired non-parametric test.
Results
The participants used M laevigata syrup primarily for COVID-19 and discomfort caused by coughing. They reported intense frequency (median 8 [range 3, 10]), intensity (10 [2, 10]), and impact of coughing on sleep (10 [0, 10]) before treatment, and significant improvements in these three characteristics after treatment (P < 0.001 for all comparisons). They also reported a quick onset effect (11%), but a few patients complained about a taste that was too sweet or unpalatable (7%).
Conclusions
Adults and children using M laevigata syrup reported significant improvements in frequency, intensity, and impact of coughing on sleep. Besides, these patients highlighted the quick effect onset and the excellent tolerability.
期刊介绍:
The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.