Analysis identifies factors associated with response to ketamine for TRD

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Abstract

Outpatient treatment initiators and individuals with moderately severe or severe pretreatment depression were most likely to benefit from ketamine treatment over electroconvulsive therapy (ECT) for treatment-resistant depression (TRD), a newly published analysis has found. Individuals with the most severe pretreatment depression saw greater benefit from ECT early in treatment. Study results were published online June 25, 2024, in JAMA Network Open.

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分析确定与氯胺酮治疗TRD反应相关的因素
一项新发表的分析发现,在治疗耐药抑郁症(TRD)时,氯胺酮治疗比电休克疗法(ECT)更能使门诊治疗启动者和治疗前患有中度或重度抑郁症的患者受益。治疗前抑郁症最严重的患者在治疗早期从电休克疗法中获益更大。研究结果于2024年6月25日在线发表在《美国医学会杂志网络版》(JAMA Network Open)上。
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