Deep learning-assisted interactive contouring of lung cancer: Impact on contouring time and consistency

IF 4.9 1区 医学 Q1 ONCOLOGY Radiotherapy and Oncology Pub Date : 2024-09-03 DOI:10.1016/j.radonc.2024.110500
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Abstract

Background and Purpose

To evaluate the impact of a deep learning (DL)-assisted interactive contouring tool on inter-observer variability and the time taken to complete tumour contouring.

Materials and Methods

Nine clinicians contoured the gross tumour volume (GTV) using the PET-CT scans of 10 non-small cell lung cancer (NSCLC) patients, either using DL-assisted or manual contouring tools. After contouring a case using one contouring method, the same case was contoured one week later using the other method. The contours and time taken were compared.

Results

Use of the DL-assisted tool led to a statistically significant decrease in active contouring time of 23 % relative to the standard manual segmentation method (p < 0.01). The mean observation time for all clinicians and cases made up nearly 60 % of interaction time for both contouring approaches. On average the time spent contouring per case was reduced from 22 min to 19 min when using the DL-assisted tool. Additionally, the DL-assisted tool reduced contour variability in the parts of tumour where clinicians tended to disagree the most, while the consensus contour was similar whichever of the two contouring approaches was used.

Conclusions

A DL-assisted interactive contouring approach decreased active contouring time and local inter-observer variability when used to delineate lung cancer GTVs compared to a standard manual method. Integration of this tool into the clinical workflow could assist clinicians in contouring tasks and improve contouring efficiency.

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深度学习辅助肺癌交互式轮廓绘制:对轮廓绘制时间和一致性的影响
背景和目的:评估深度学习(DL)辅助的交互式轮廓工具对观察者间差异和完成肿瘤轮廓绘制所需时间的影响:九名临床医生使用DL辅助或手动轮廓工具,利用10名非小细胞肺癌(NSCLC)患者的PET-CT扫描结果对肿瘤总体积(GTV)进行轮廓分析。使用一种轮廓绘制方法绘制病例轮廓后,一周后再使用另一种方法绘制同一病例的轮廓。结果:结果:使用 DL 辅助工具后,主动轮廓绘制时间比标准手动分割方法显著减少了 23%(p 结论:使用 DL 辅助交互式轮廓绘制工具,能显著减少主动轮廓绘制时间:与标准手动方法相比,使用 DL 辅助交互式轮廓划分方法划分肺癌 GTV 时,可减少主动轮廓划分时间和局部观察者间的变异性。将这一工具整合到临床工作流程中可以帮助临床医生完成轮廓绘制任务,提高轮廓绘制效率。
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来源期刊
Radiotherapy and Oncology
Radiotherapy and Oncology 医学-核医学
CiteScore
10.30
自引率
10.50%
发文量
2445
审稿时长
45 days
期刊介绍: Radiotherapy and Oncology publishes papers describing original research as well as review articles. It covers areas of interest relating to radiation oncology. This includes: clinical radiotherapy, combined modality treatment, translational studies, epidemiological outcomes, imaging, dosimetry, and radiation therapy planning, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as data science in radiation oncology and physics aspects relevant to oncology.Papers on more general aspects of interest to the radiation oncologist including chemotherapy, surgery and immunology are also published.
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