GLABRA2 transcription factor integrates arsenic tolerance with epidermal cell fate determination

IF 8.1 1区 生物学 Q1 PLANT SCIENCES New Phytologist Pub Date : 2024-09-05 DOI:10.1111/nph.20099
Micaela Andrea Navarro, Cristina Navarro, Luis Eduardo Hernández, María Garnica, José Manuel Franco-Zorrilla, Yogev Burko, Sara González-Serrano, José M. García-Mina, José Pruneda-Paz, Joanne Chory, Antonio Leyva
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GLABRA2 转录因子将砷耐受性与表皮细胞命运决定结合在一起。
砷对生物体构成全球性威胁,危及作物安全和产量。由于对砷耐受机制与植物发育反应相结合的转录网络了解有限,阻碍了针对这种有毒类金属的策略的开发。在这里,我们使用拟南芥砷诱导基因 ARQ1 和 ASK18 的启动子区作为诱饵,结合转录组分析,进行了高通量酵母单杂交试验,以发现砷反应的新型转录调控因子。我们发现 GLABRA2(GL2)转录因子是砷耐受性的新型调控因子,揭示了其除了作为根毛形成抑制因子的既定功能外,还具有更广泛的调控作用。此外,我们还发现 GL2 亚家族成员 ANTHOCYANINLESS2(ANL2)与该转录因子在砷信号转导调控中起着冗余作用。这两个转录因子都是砷反应的抑制因子。gl2和anl2突变体表现出更强的耐受性和更低的砷积累。对 gl2 突变体的转录分析揭示了砷耐受性的潜在调节因子。这些发现突出表明,GL2 和 ANL2 是砷反应与发育结果的新型整合因子,为开发砷含量更低、对这种有害类金属耐受性更强的更安全作物提供了启示。
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来源期刊
New Phytologist
New Phytologist 生物-植物科学
自引率
5.30%
发文量
728
期刊介绍: New Phytologist is an international electronic journal published 24 times a year. It is owned by the New Phytologist Foundation, a non-profit-making charitable organization dedicated to promoting plant science. The journal publishes excellent, novel, rigorous, and timely research and scholarship in plant science and its applications. The articles cover topics in five sections: Physiology & Development, Environment, Interaction, Evolution, and Transformative Plant Biotechnology. These sections encompass intracellular processes, global environmental change, and encourage cross-disciplinary approaches. The journal recognizes the use of techniques from molecular and cell biology, functional genomics, modeling, and system-based approaches in plant science. Abstracting and Indexing Information for New Phytologist includes Academic Search, AgBiotech News & Information, Agroforestry Abstracts, Biochemistry & Biophysics Citation Index, Botanical Pesticides, CAB Abstracts®, Environment Index, Global Health, and Plant Breeding Abstracts, and others.
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