Optimizing COVID-19 testing resources use with wearable sensors.

PLOS digital health Pub Date : 2024-09-05 eCollection Date: 2024-09-01 DOI:10.1371/journal.pdig.0000584
Giorgio Quer, Arinbjörn Kolbeinsson, Jennifer M Radin, Luca Foschini, Jay Pandit
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Abstract

The timely identification of infectious pre-symptomatic and asymptomatic cases is key towards preventing the spread of a viral illness like COVID-19. Early identification has been done through routine testing programs, which are indeed costly and potentially burdensome for individuals who should be tested with high frequency. A supplemental tool is represented by wearable technology, that can passively monitor and identify individuals at high risk, alerting them to take a test. We designed a Markov chain model and simulated a routine testing and a wearable testing strategy to estimate the number of tests required and the average number of days in which an individual is infectious and undetected. According to our model, with 2 test per month available, we have that the number of infectious and undetected days is 4.1 in the case of routine testing, while it decreases by 46% and 27% with a wearable testing strategy in the presence or absence of self-reported symptoms. The proposed parametric model can be used for different viral illnesses by tuning its parameters. It shows that wearable technology informing a testing strategy can significantly reduce the number of infectious days in which an individuals can spread the virus. With the same number of infectious days, by using wearables we can potentially reduce the number of required tests and the cost of the testing strategy.

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优化 COVID-19 测试资源与可穿戴传感器的配合使用。
及时发现无症状和无症状的传染性病例是防止 COVID-19 等病毒性疾病传播的关键。通过常规检测项目可以及早发现病例,但这些项目成本高昂,而且可能会给需要频繁接受检测的人带来负担。可穿戴技术是一种补充工具,它可以被动监测和识别高危人群,提醒他们接受检测。我们设计了一个马尔科夫链模型,并模拟了常规检测和可穿戴检测策略,以估算所需的检测次数以及感染者未被发现的平均天数。根据我们的模型,在每月可进行 2 次检测的情况下,常规检测的感染和未检测天数为 4.1 天,而采用可穿戴检测策略时,无论有无自我报告症状,感染和未检测天数分别减少了 46% 和 27%。通过调整参数,所提出的参数模型可用于不同的病毒性疾病。结果表明,可穿戴技术为检测策略提供信息,可以大大减少个人传播病毒的感染天数。在传染天数相同的情况下,通过使用可穿戴设备,我们有可能减少所需的检测次数和检测策略的成本。
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