Experimental study of contrast-enhanced ultrasound in the evaluation of random-pattern flap blood supply in the early postoperative stage in rats.

IF 1 4区医学 Q3 ORTHOPEDICS Journal of Plastic Surgery and Hand Surgery Pub Date : 2024-09-09 DOI:10.2340/jphs.v59.39975

Jian-Xun Ma, You-Chen Xia, Zhi-Yong Bai, Hua-Bin Zhang, Xia Xie

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Abstract

Purpose: This study aims to investigate whether contrast-enhanced ultrasound (CEUS) could be used to reveal the status of blood supply of the superficial flap of rat model in the early postoperative stage.

Methods: One viable and one ischemic random-pattern flap were prepared on the left and right back of the same rat respectively with a number of 40. CEUS examinations were applied within 12 h and 7 days postoperatively, and the quantitative measurements of microvascular blood volume (BV) of the base and the end of both flaps were expressed using acoustic intensity as a ratio to that of the healthy skin.

Results: Within 12 h post operation, there was a smaller BV value of the ischemic ends than that of both the ischemic bases and viable ends (p < 0.001), while no difference was indicated between ischemic bases and viable bases or between viable bases and viable ends. The same result was provided 7 days post operation.

Conclusion: Microcirculation of superficial tissues such as random-pattern flaps in this rat model can be assessed quantitatively by CEUS. It could sensitively and accurately reveal the objective status of tissue perfusion in the early postoperative stage.

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对比增强超声波在大鼠术后早期评估随机模式皮瓣供血的实验研究。

目的：本研究旨在探讨对比增强超声（CEUS）是否可用于揭示大鼠模型浅表皮瓣术后早期的血供状况：方法：在同一只大鼠的左背部和右背部分别制备一个存活和一个缺血的随机模式皮瓣，数量为 40 个。方法：在同一只大鼠的左背部和右背部分别制备一个存活的和一个缺血的随机图案皮瓣，数量为 40 个，分别在术后 12 小时和 7 天内进行 CEUS 检查，用声强与健康皮肤的比值来表示两个皮瓣基底和末端微血管血容量（BV）的定量测量结果：结果：术后 12 小时内，缺血末端的 BV 值小于缺血基底和存活末端的 BV 值（p 结论：术后 12 小时内，缺血基底和存活末端的 BV 值均小于缺血基底和存活末端的 BV 值：该大鼠模型中随机模式皮瓣等浅表组织的微循环可通过 CEUS 进行定量评估。它可以灵敏、准确地揭示术后早期组织灌注的客观状况。

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来源期刊

Journal of Plastic Surgery and Hand Surgery ORTHOPEDICS-SURGERY

CiteScore

2.10

自引率

0.00%

发文量

108

审稿时长

6-12 weeks

期刊介绍： The purpose of the Journal of Plastic Surgery and Hand Surgery is to serve as an international forum for plastic surgery, hand surgery and related research. Interest is focused on original articles on basic research and clinical evaluation. The scope of the journal comprises: • Articles concerning operative methods and follow-up studies • Research articles on subjects related to plastic and hand surgery • Articles on cranio-maxillofacial surgery, including cleft lip and palate surgery. Extended issues are published occasionally, dealing with special topics such as microvascular surgery, craniofacial surgery, or burns. Supplements, usually doctoral theses, may also be published. The journal is published for the Acta Chirurgica Scandinavica society and sponsored by the Key Foundation, Sweden. The journal was previously published as Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery.