Average treatment effect on the treated, under lack of positivity.

IF 1.6 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Statistical Methods in Medical Research Pub Date : 2024-10-01 Epub Date: 2024-09-09 DOI:10.1177/09622802241269646
Yi Liu, Huiyue Li, Yunji Zhou, Roland A Matsouaka
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Abstract

The use of propensity score methods has become ubiquitous in causal inference. At the heart of these methods is the positivity assumption. Violation of the positivity assumption leads to the presence of extreme propensity score weights when estimating average causal effects, which affects statistical inference. To circumvent this issue, trimming or truncating methods have been widely used. Unfortunately, these methods require that we pre-specify a threshold. There are a number of alternative methods to deal with the lack of positivity when we estimate the average treatment effect (ATE). However, no other methods exist beyond trimming and truncation to deal with the same issue when the goal is to estimate the average treatment effect on the treated (ATT). In this article, we propose a propensity score weight-based alternative for the ATT, called overlap weighted average treatment effect on the treated. The appeal of our proposed method lies in its ability to obtain similar or even better results than trimming and truncation while relaxing the constraint to choose an a priori threshold (or related measures). The performance of the proposed method is illustrated via a series of Monte Carlo simulations and a data analysis on racial disparities in health care expenditures.

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在缺乏积极性的情况下,对被治疗者的平均治疗效果。
在因果推断中,倾向得分法的使用已变得无处不在。这些方法的核心是积极性假设。违反积极性假设会导致在估计平均因果效应时出现极端倾向得分权重,从而影响统计推断。为了规避这一问题,修剪或截断方法得到了广泛应用。遗憾的是,这些方法要求我们预先指定一个阈值。当我们估计平均治疗效果(ATE)时,有许多替代方法可以解决缺乏正向性的问题。然而,当我们的目标是估计平均治疗效果(ATT)时,除了修剪和截断外,还没有其他方法来解决同样的问题。在本文中,我们提出了一种基于倾向得分权重的 ATT 替代方法,称为 "重叠加权平均治疗效果"。我们提出的方法的吸引力在于,它能够获得与修剪和截断相似甚至更好的结果,同时放宽了选择先验阈值(或相关测量方法)的限制。我们通过一系列蒙特卡罗模拟和医疗支出种族差异的数据分析来说明所提方法的性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Statistical Methods in Medical Research
Statistical Methods in Medical Research 医学-数学与计算生物学
CiteScore
4.10
自引率
4.30%
发文量
127
审稿时长
>12 weeks
期刊介绍: Statistical Methods in Medical Research is a peer reviewed scholarly journal and is the leading vehicle for articles in all the main areas of medical statistics and an essential reference for all medical statisticians. This unique journal is devoted solely to statistics and medicine and aims to keep professionals abreast of the many powerful statistical techniques now available to the medical profession. This journal is a member of the Committee on Publication Ethics (COPE)
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