Visualizing mitochondrial dynamics at the nanoscale

IF 20.6 Q1 OPTICS Light-Science & Applications Pub Date : 2024-09-09 DOI:10.1038/s41377-024-01582-3
Till Stephan, Peter Ilgen, Stefan Jakobs
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Abstract

The study of mitochondria is a formidable challenge for super-resolution microscopy due to their dynamic nature and complex membrane architecture. In this issue, Ren et al. introduce HBmito Crimson, a fluorogenic and photostable mitochondrial probe for STED microscopy and investigate how mitochondrial dynamics influence the spatial organization of mitochondrial DNA.

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纳米级线粒体动态可视化
由于线粒体的动态性质和复杂的膜结构,对其进行研究是超分辨率显微镜的一项艰巨挑战。在本期中,Ren 等人介绍了用于 STED 显微镜的线粒体探针 HBmito Crimson,它是一种荧光性和光稳性线粒体探针,研究了线粒体动力学如何影响线粒体 DNA 的空间组织。
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来源期刊
Light-Science & Applications
Light-Science & Applications 数理科学, 物理学I, 光学, 凝聚态物性 II :电子结构、电学、磁学和光学性质, 无机非金属材料, 无机非金属类光电信息与功能材料, 工程与材料, 信息科学, 光学和光电子学, 光学和光电子材料, 非线性光学与量子光学
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803
审稿时长
2.1 months
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