The effect of Momordica charantia extract on sheep infected with Haemonchus contortus

IF 2.2 3区农林科学 Q1 VETERINARY SCIENCES Research in veterinary science Pub Date : 2024-09-04 DOI:10.1016/j.rvsc.2024.105401

Ana Maria de Jesus Teixeira Alves , Laura Lúcia dos Santos Oliveira , Gabriele Lorrane Santos Silva , Maura Elis Oliveira Dornelas , Marcos Flávio Silveira Vasconcelos D'Angelo , Denilson Ferreira de Oliveira , Walter dos Santos Lima , Cíntia Aparecida de Jesus Pereira , Fredson Vieira e Silva

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Abstract

Bitter melon (Momordica charantia) has several biological properties including anthelmintic activity. Presented in vivo study evaluated the anthelmintic activity of the hydroalcoholic extract of M. charantia Presented in vivo study (HEMC) and its effect on animal performance, carcass characteristics and lamb meat quality in animals infected by Haemonchus contortus. The HEMC demonstrated effectiveness against the parasite. Lambs treated with HEMC showed a significant reduction in egg count per gram of faeces and in the number of parasites in the abomasum. However, nutrient intake decreased with increasing doses of HEMC, leading to reductions in final live weight and carcass weight. No significant effects were observed on meat quality. Therefore, it is concluded that HEMC presents anthelmintic action, but it also impairs animal performance, highlighting the need to assess the benefits and impacts of HEMC use for H. contortus control.

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山慈姑提取物对感染传染性单核细胞增多症的绵羊的影响

苦瓜（Momordica charantia）具有多种生物特性，包括驱虫活性。这项体内研究评估了苦瓜水醇提取物（HEMC）的驱虫活性，以及它对感染传染性单核细胞增多症（Haemonchus contortus）的动物的表现、胴体特征和羔羊肉质的影响。HEMC 对寄生虫有很好的效果。接受 HEMC 治疗的羔羊每克粪便中的虫卵数和腹腔中的寄生虫数量均显著减少。然而，营养摄入量随着 HEMC 剂量的增加而减少，导致最终活重和胴体重量下降。没有观察到对肉质有明显影响。因此，得出的结论是，HEMC 具有驱虫作用，但也会损害动物的生产性能，因此需要评估使用 HEMC 控制 H. contortus 的益处和影响。

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来源期刊

Research in veterinary science 农林科学-兽医学

CiteScore

4.40

自引率

4.20%

发文量

312

审稿时长

75 days

期刊介绍： Research in Veterinary Science is an International multi-disciplinary journal publishing original articles, reviews and short communications of a high scientific and ethical standard in all aspects of veterinary and biomedical research. The primary aim of the journal is to inform veterinary and biomedical scientists of significant advances in veterinary and related research through prompt publication and dissemination. Secondly, the journal aims to provide a general multi-disciplinary forum for discussion and debate of news and issues concerning veterinary science. Thirdly, to promote the dissemination of knowledge to a broader range of professions, globally. High quality papers on all species of animals are considered, particularly those considered to be of high scientific importance and originality, and with interdisciplinary interest. The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health. Studies without a robust scientific hypothesis or that are preliminary, or of weak originality, as well as negative results, are not appropriate for the journal. Furthermore, observational approaches, case studies or field reports lacking an advancement in general knowledge do not fall within the scope of the journal.