Kristina Coulter, Natalie A. Phillips, the CIMA-Q and COMPASS-ND groups
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引用次数: 0
Abstract
We examined brain and cognitive reserve related to bilingualism in older adults with, or at-risk for, Alzheimer's disease (AD) from the Canadian Consortium on Neurodegeneration in Aging and the Quebec Consortium for the Early Identification of Alzheimer's Disease. We used surface-based morphometry methods to measure cortical thickness and volume of language-related and AD-related brain regions. We did not observe evidence of brain reserve in language-related regions. However, reduced hippocampal volume was observed for monolingual, but not bilingual, older adults with AD. Thus, bilingualism is hypothesized to contribute to reserve in the form of brain maintenance in the context of AD.
我们研究了加拿大老龄化神经变性联合会（Canadian Consortium on Neurodegeneration in Aging）和魁北克阿尔茨海默病早期识别联合会（Quebec Consortium for the Early Identification of Alzheimer's Disease）中患有阿尔茨海默病（AD）或有此风险的老年人的大脑和认知储备与双语能力的关系。我们采用了基于表面形态测量的方法来测量与语言相关和与阿兹海默症相关的大脑区域的皮质厚度和体积。我们没有在语言相关区域观察到大脑储备的证据。然而，我们观察到患有注意力缺失症的单语老年人的海马体积减小，而双语老年人的海马体积却没有减小。因此，我们推测双语有助于在注意力缺失症的情况下以大脑维护的形式促进大脑储备。
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