The use of hyperinsulinemia‐euglycaemia therapy in the treatment of amlodipine overdose in a dog

IF 0.3 Q4 VETERINARY SCIENCES Veterinary Record Case Reports Pub Date : 2024-08-12 DOI:10.1002/vrc2.955
Connor Ellis, Adesola Odunayo
{"title":"The use of hyperinsulinemia‐euglycaemia therapy in the treatment of amlodipine overdose in a dog","authors":"Connor Ellis, Adesola Odunayo","doi":"10.1002/vrc2.955","DOIUrl":null,"url":null,"abstract":"A 1‐year‐old, female, spayed, mixed breed dog presented for lethargy, ataxia and possible ingestion of amlodipine. Based on clinical signs, history and clinicopathological findings, a diagnosis of amlodipine toxicosis was made. The patient's clinical signs and bloodwork derangements were refractory to traditional medical management for calcium channel blocker toxicosis, but a significant improvement was made after initiation of hyperinsulinemia‐euglycaemia therapy. The dog survived and made a full recovery. The use of hyperinsulinemia‐euglycaemia therapy for amlodipine toxicosis has not previously been reported in dogs. Hyperinsulinemia‐euglycaemia therapy can be used for treatment of hypotension as well as other clinical signs associated with calcium channel blocker toxicosis. The use of hyperinsulinemia‐euglycaemia therapy should be considered for amlodipine toxicosis in dogs.","PeriodicalId":23496,"journal":{"name":"Veterinary Record Case Reports","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Record Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/vrc2.955","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

A 1‐year‐old, female, spayed, mixed breed dog presented for lethargy, ataxia and possible ingestion of amlodipine. Based on clinical signs, history and clinicopathological findings, a diagnosis of amlodipine toxicosis was made. The patient's clinical signs and bloodwork derangements were refractory to traditional medical management for calcium channel blocker toxicosis, but a significant improvement was made after initiation of hyperinsulinemia‐euglycaemia therapy. The dog survived and made a full recovery. The use of hyperinsulinemia‐euglycaemia therapy for amlodipine toxicosis has not previously been reported in dogs. Hyperinsulinemia‐euglycaemia therapy can be used for treatment of hypotension as well as other clinical signs associated with calcium channel blocker toxicosis. The use of hyperinsulinemia‐euglycaemia therapy should be considered for amlodipine toxicosis in dogs.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
使用高胰岛素血症-高血糖疗法治疗狗体内氨氯地平过量
一只 1 岁大的雌性混种犬因嗜睡、共济失调和可能误食氨氯地平而就诊。根据临床症状、病史和临床病理结果,诊断为氨氯地平中毒。传统的钙通道阻滞剂中毒治疗方法对患者的临床症状和血液检查结果无效,但在开始使用高胰岛素血症-血糖治疗后,情况有了明显改善。该犬得以存活并完全康复。在犬只中使用高胰岛素血症-高血糖疗法治疗氨氯地平中毒症的情况以前从未报道过。高胰岛素血症-高血糖疗法可用于治疗低血压以及与钙通道阻滞剂中毒相关的其他临床症状。犬氨氯地平中毒症应考虑使用高胰岛素血症-高血糖疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Veterinary Record Case Reports
Veterinary Record Case Reports Veterinary-Veterinary (all)
CiteScore
0.50
自引率
33.30%
发文量
266
期刊介绍: Vet Record Case Reports is an online resource that publishes articles in all fields of veterinary medicine and surgery so that veterinary professionals, researchers and others can easily find important information on both common and rare conditions. Articles may be about a single animal, herd, flock or other group of animals managed together. Common cases that present a diagnostic, ethical or management challenge, or that highlight aspects of mechanisms of injury, pharmacology or histopathology are deemed of particular educational value. All articles are peer reviewed and copy edited before publication.
期刊最新文献
Metastatic cholangiocarcinoma in a cow presenting as suspect bovine tuberculosis in Ireland Bovine abortion caused by leptospirosis Phaeohyphomycosis caused by Trematosphaeria grisea in an immunocompromised English springer spaniel Nociceptive threshold measurement as a non‐invasive functional test of an epidural injection in a dog Intraocular malignant nerve sheath tumour in a brown eyed labrador retriever
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1