Tianyuan Lu, Wenmin Zhang, Cassianne Robinson-Cohen, Corinne D. Engelman, Qiongshi Lu, Ian H. de Boer, Lei Sun, Andrew D. Paterson
{"title":"Improved characterization of gene-environment interactions for vitamin D through variance quantitative trait loci","authors":"Tianyuan Lu, Wenmin Zhang, Cassianne Robinson-Cohen, Corinne D. Engelman, Qiongshi Lu, Ian H. de Boer, Lei Sun, Andrew D. Paterson","doi":"10.1101/2024.08.30.24312868","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Understanding gene-environment interaction effects influencing vitamin D status may refine nutrition and public health strategies for vitamin D deficiency. Recent methodological advances have enabled the identification of variance quantitative trait loci (vQTLs) where gene-environment interaction effects are enriched.","PeriodicalId":501375,"journal":{"name":"medRxiv - Genetic and Genomic Medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Genetic and Genomic Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.08.30.24312868","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background Understanding gene-environment interaction effects influencing vitamin D status may refine nutrition and public health strategies for vitamin D deficiency. Recent methodological advances have enabled the identification of variance quantitative trait loci (vQTLs) where gene-environment interaction effects are enriched.
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