Selective cross-hydrodimerization of alkenes

N/A CHEMISTRY, MULTIDISCIPLINARY Nature synthesis Pub Date : 2024-09-09 DOI:10.1038/s44160-024-00635-0
Sudip Maiti, Debabrata Maiti
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Abstract

Enantioenriched alkyl–alkyl bonds are produced from abundant alkenes in one step via Ni-catalysed asymmetric cross-hydrodimerization. This technique overcomes the reactivity and selectivity challenges associated with coupling between two similar nucleophiles.

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烯烃的选择性交叉二聚化
通过镍催化的不对称交叉二聚氢反应,一步即可从丰富的烯烃中生成对映体烷基-烷基键。该技术克服了两个类似亲核物之间耦合所带来的反应性和选择性难题。
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