Quantifying the social value of a universal COVID-19 vaccine and incentivizing its development

IF 0.3 4区 经济学 Q4 ECONOMICS Review of Economic Design Pub Date : 2024-08-30 DOI:10.1007/s10058-024-00363-z
Rachel Glennerster, Thomas Kelly, Claire T. McMahon, Christopher M. Snyder
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Abstract

Booster shots for COVID-19 vaccines in the United States have undergone periodic updates to target circulating variants. However, the lengthy process of development, testing, and production has resulted lags between a variant’s initial detection and the corresponding booster's rollout, by which time the booster may no longer match the circulating variant. An innovation with realistic scientific potential—a universal COVID-19 vaccine, effective against existing and future variants—could provide much more value by preempting new variants. Averaged across Monte Carlo simulations, we estimate that, even under conservative assumptions on the arrival rate of variants, a universal COVID-19 vaccine would increase health benefits over variant-specific boosters by more than $900 billion. This social value eclipses the cost of an advance market commitment to incentivize the universal vaccine by several orders of magnitude.

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量化通用 COVID-19 疫苗的社会价值并激励其开发
美国对 COVID-19 疫苗的加强针进行了定期更新,以针对流行变种。然而,漫长的研发、测试和生产过程导致变种首次被检测到与相应的加强针推出之间出现滞后,届时加强针可能已不再与流行变种相匹配。一种具有现实科学潜力的创新--对现有和未来变种都有效的通用 COVID-19 疫苗--可以通过抢先发现新变种而带来更大的价值。根据蒙特卡洛模拟的平均值,我们估计,即使在变异株出现率的保守假设下,COVID-19 疫苗的通用性也会比针对特定变异株的疫苗增加 9000 多亿美元的健康效益。这一社会价值超过了为激励普及疫苗而提前作出市场承诺的成本,达到了几个数量级。
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来源期刊
CiteScore
0.80
自引率
28.60%
发文量
37
期刊介绍: Review of Economic Design comprises the creative art and science of inventing, analyzing and testing economic as well as social and political institutions and mechanisms aimed at achieving individual objectives and social goals. In this age of Economic Design, the accumulated traditions and wealth of knowledge in normative and positive economics and the strategic analysis of game theory are applied with novel ideas in the creative tasks of designing and assembling diverse legal-economic instruments. These include constitutions and other assignments of rights, mechanisms for allocation or regulation, tax and incentive schemes, contract forms, voting and other choice aggregation procedures, markets, auctions, organizational forms, such as partnerships, together with supporting membership and other property rights, and information systems. These designs, the methods of analysis used in their scrutiny, as well as the mathematical techniques and empirical knowledge they employ, along with comparative assessments of the performance of known economic systems and implemented designs, all of these form natural components of the subject matter of Economic Design. Officially cited as: Rev Econ Design
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