Changes in the HIV Epidemic in Lower Silesia, Poland, Between 2010 and 2020: The Characteristics of the Key Populations

Viruses Pub Date : 2024-09-11 DOI:10.3390/v16091445
Aleksandra Kozieł, Aleksandra Cieślik, Łucja Janek, Aleksandra Szymczak, Igor Domański, Brygida Knysz, Bartosz Szetela
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Abstract

The HIV (Human Immunodeficiency Virus) epidemic remains a significant public health issue, requiring ongoing access to preventive methods. This study aimed to analyze the evolution of the HIV epidemic in Lower Silesia from 2010 to 2020, focusing on the key populations. A retrospective analysis of the medical records from newly diagnosed HIV patients at a major HIV clinic in Wroclaw was conducted, examining demographic data, infection routes, and laboratory results. An 84% increase in newly diagnosed HIV cases was observed over the decade, with the most common route of infection being sex between men (70% among those with a known infection route). These patients were generally in better clinical condition compared to their heterosexual counterparts, as indicated by a higher median CD4+ T cell count (465/μL vs. 250/μL). The changes in clinical status and infection routes were statistically significant. The HIV epidemic in Lower Silesia has shifted, with a notable rise in new infections among men who have sex with men. Heterosexual patients were often diagnosed at more advanced stages. Prevention strategies should adapt to these changing trends, with education and testing accessibility remaining priorities nationwide.
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2010 年至 2020 年期间波兰下西里西亚地区艾滋病疫情的变化:主要人群的特征
艾滋病毒(人类免疫缺陷病毒)疫情仍然是一个重大的公共卫生问题,需要不断获得预防方法。本研究旨在分析 2010 年至 2020 年下西里西亚地区艾滋病疫情的演变情况,重点关注主要人群。研究人员对弗罗茨瓦夫一家大型艾滋病诊所新诊断出的艾滋病患者的病历进行了回顾性分析,研究了人口统计学数据、感染途径和实验室结果。在过去十年中,新诊断的艾滋病病例增加了 84%,最常见的感染途径是男男性行为(在已知感染途径的病例中占 70%)。与异性恋患者相比,这些患者的临床状况普遍较好,CD4+ T 细胞计数中位数较高(465/μL 对 250/μL)就说明了这一点。临床状况和感染途径的变化具有统计学意义。下西里西亚的艾滋病疫情发生了变化,男男性行为者中的新感染病例明显增加。异性恋患者通常在确诊时已处于晚期。预防战略应适应这些变化趋势,教育和检测的可及性仍是全国范围内的优先事项。
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