Y. A. Nashchekina, V. A. Konson, M. Y. Sirotkina, A. V. Nashchekin
{"title":"Structure and Stability of Composite Gels Based on Collagen and Carboxymethylcellulose","authors":"Y. A. Nashchekina, V. A. Konson, M. Y. Sirotkina, A. V. Nashchekin","doi":"10.1134/s1063784224010298","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10–30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.</p>","PeriodicalId":783,"journal":{"name":"Technical Physics","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Technical Physics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1134/s1063784224010298","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10–30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.
期刊介绍：
Technical Physics is a journal that contains practical information on all aspects of applied physics, especially instrumentation and measurement techniques. Particular emphasis is put on plasma physics and related fields such as studies of charged particles in electromagnetic fields, synchrotron radiation, electron and ion beams, gas lasers and discharges. Other journal topics are the properties of condensed matter, including semiconductors, superconductors, gases, liquids, and different materials.
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