{"title":"Tunable structural, optical and bioactive properties of magnesium and bismuth co-doping on bioactive glass nanoparticles for biomedical applications","authors":"Divya Goel, Deenan Santhiya","doi":"10.1557/s43578-024-01433-2","DOIUrl":null,"url":null,"abstract":"<p>The current study focused to synthesize magnesium (Mg<sup>2+</sup>) and bismuth (Bi<sup>3+</sup>) co-doped bioactive glass (BG) nanoparticles (NPs) at ambient conditions. XPS studies confirmed the existence of Mg<sup>2+</sup> as MgO and Bi<sup>3+</sup> as Bi<sub>2</sub>O<sub>3</sub> in co-doped BG NPs. XRD reported an increase in mean crystallite size from 0.1 ± 0.01 nm to 0.25 ± 0.04 nm with 0.5 to 1.5 mol% increase in Bi<sub>2</sub>O<sub>3</sub> content. TGA revealed co-doping of Mg<sup>2+</sup> and Bi<sup>3+</sup> to BG NPs increased their thermal stability by 20 to 30 w/w% in comparison to the control. FTIR and NMR studies depicted open SiO<sub>2</sub> network in co-doped BG NPs. HR-TEM evidenced co-doped BG NPs were of ~ 50 nm. The optical transmittance showed strong emission peak at 480 nm for co-doped BG NPs with decreased intensity with increasing Bi<sup>3+</sup> ion concentration. In-vitro bioactivity, hemolysis and MTT assay revealed excellent bone binding ability, least toxicity and excellent biocompatibility.</p><h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>\n","PeriodicalId":16306,"journal":{"name":"Journal of Materials Research","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Materials Research","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1557/s43578-024-01433-2","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The current study focused to synthesize magnesium (Mg2+) and bismuth (Bi3+) co-doped bioactive glass (BG) nanoparticles (NPs) at ambient conditions. XPS studies confirmed the existence of Mg2+ as MgO and Bi3+ as Bi2O3 in co-doped BG NPs. XRD reported an increase in mean crystallite size from 0.1 ± 0.01 nm to 0.25 ± 0.04 nm with 0.5 to 1.5 mol% increase in Bi2O3 content. TGA revealed co-doping of Mg2+ and Bi3+ to BG NPs increased their thermal stability by 20 to 30 w/w% in comparison to the control. FTIR and NMR studies depicted open SiO2 network in co-doped BG NPs. HR-TEM evidenced co-doped BG NPs were of ~ 50 nm. The optical transmittance showed strong emission peak at 480 nm for co-doped BG NPs with decreased intensity with increasing Bi3+ ion concentration. In-vitro bioactivity, hemolysis and MTT assay revealed excellent bone binding ability, least toxicity and excellent biocompatibility.
期刊介绍：
Journal of Materials Research (JMR) publishes the latest advances about the creation of new materials and materials with novel functionalities, fundamental understanding of processes that control the response of materials, and development of materials with significant performance improvements relative to state of the art materials. JMR welcomes papers that highlight novel processing techniques, the application and development of new analytical tools, and interpretation of fundamental materials science to achieve enhanced materials properties and uses. Materials research papers in the following topical areas are welcome.
• Novel materials discovery
• Electronic, photonic and magnetic materials
• Energy Conversion and storage materials
• New thermal and structural materials
• Soft materials
• Biomaterials and related topics
• Nanoscale science and technology
• Advances in materials characterization methods and techniques
• Computational materials science, modeling and theory
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