{"title":"Erythrocyte Osmotic Fragility as A Diagnostic Marker in Glaucoma: A Comprehensive Analysis Using LASSO Regression","authors":"Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang","doi":"10.1101/2024.09.05.24312988","DOIUrl":null,"url":null,"abstract":"<strong>Objective</strong> This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.","PeriodicalId":501390,"journal":{"name":"medRxiv - Ophthalmology","volume":"59 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.09.05.24312988","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.
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