Sorption of pharmaceutically active compounds to soils: a review

IF 6 3区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Environmental Sciences Europe Pub Date : 2024-09-11 DOI:10.1186/s12302-024-00984-9
Ahmad M. Alhalabi, Mohammed A. Meetani, Ahmad Shabib, Munjed A. Maraqa
{"title":"Sorption of pharmaceutically active compounds to soils: a review","authors":"Ahmad M. Alhalabi,&nbsp;Mohammed A. Meetani,&nbsp;Ahmad Shabib,&nbsp;Munjed A. Maraqa","doi":"10.1186/s12302-024-00984-9","DOIUrl":null,"url":null,"abstract":"<div><p>Pharmaceutically active compounds (PACs) are ubiquitous contaminants that can pollute the environment. This study critically analyzes the sorption of PACs to soil materials based on 137 published papers encompassing 106 PACs and 212 soil materials. The batch technique is commonly employed for sorption studies of PACs to soil, but the experimental setups vary in terms of the type and number of PACs, mixing time, solid to liquid (S/L) ratio, solution type, range of initial concentration, and bio-inhibition method. Sorption competition among PACs or between PACs and dissolved organic matter occurs for certain cases. Linear or close to linear behavior was reported for sorption of many PACs to soil, but sorption of some PACs deviates from linearity. The reaction of PACs to soil is fast at the initial stages but slows down as it approaches equilibrium. PACs characteristics, soil properties, and solution attributes intricately influence the sorption process. Zwitterionic PACs exhibit the highest sorption affinity, whereas neutral PACs display increased sensitivity to soil hydrophobicity. The average sorption coefficient (K) ranges from 0.0915 mL/g for anionic sulfonamides to 84725.5 mL/g for zwitterionic norfloxacin. An increase in the molar volume corresponds to heightened sorption for cationic PACs and reduced sorption for anionic PACs. Increasing solubility, soil organic carbon, cation exchange capacity, S/L ratio, and soil surface area while decreasing pH, ionic strength, and temperature result in an increase in K. The values of K determined by the batch technique are higher than their column-determined counterparts, possibly due to variations in the employed residence times between the two systems. Several models have been developed to estimate K of PACs, but they are limited in their applicability to specific PACs and soil types. Future research related to sorption of PACs to soils has been suggested.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":null,"pages":null},"PeriodicalIF":6.0000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-024-00984-9.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Sciences Europe","FirstCategoryId":"93","ListUrlMain":"https://link.springer.com/article/10.1186/s12302-024-00984-9","RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Pharmaceutically active compounds (PACs) are ubiquitous contaminants that can pollute the environment. This study critically analyzes the sorption of PACs to soil materials based on 137 published papers encompassing 106 PACs and 212 soil materials. The batch technique is commonly employed for sorption studies of PACs to soil, but the experimental setups vary in terms of the type and number of PACs, mixing time, solid to liquid (S/L) ratio, solution type, range of initial concentration, and bio-inhibition method. Sorption competition among PACs or between PACs and dissolved organic matter occurs for certain cases. Linear or close to linear behavior was reported for sorption of many PACs to soil, but sorption of some PACs deviates from linearity. The reaction of PACs to soil is fast at the initial stages but slows down as it approaches equilibrium. PACs characteristics, soil properties, and solution attributes intricately influence the sorption process. Zwitterionic PACs exhibit the highest sorption affinity, whereas neutral PACs display increased sensitivity to soil hydrophobicity. The average sorption coefficient (K) ranges from 0.0915 mL/g for anionic sulfonamides to 84725.5 mL/g for zwitterionic norfloxacin. An increase in the molar volume corresponds to heightened sorption for cationic PACs and reduced sorption for anionic PACs. Increasing solubility, soil organic carbon, cation exchange capacity, S/L ratio, and soil surface area while decreasing pH, ionic strength, and temperature result in an increase in K. The values of K determined by the batch technique are higher than their column-determined counterparts, possibly due to variations in the employed residence times between the two systems. Several models have been developed to estimate K of PACs, but they are limited in their applicability to specific PACs and soil types. Future research related to sorption of PACs to soils has been suggested.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
土壤对药物活性化合物的吸附:综述
药物活性化合物 (PAC) 是一种无处不在的污染物,会对环境造成污染。本研究基于已发表的 137 篇论文(包括 106 种 PAC 和 212 种土壤材料),对 PAC 对土壤材料的吸附进行了批判性分析。PACs 对土壤的吸附研究通常采用间歇技术,但实验设置在 PACs 的类型和数量、混合时间、固液比(S/L)、溶液类型、初始浓度范围和生物抑制方法等方面各不相同。在某些情况下,PAC 之间或 PAC 与溶解有机物之间会发生吸附竞争。据报道,许多 PAC 对土壤的吸附呈线性或接近线性,但有些 PAC 的吸附则偏离了线性。PAC 与土壤的反应在初始阶段速度很快,但在接近平衡时速度会减慢。PAC 的特性、土壤性质和溶液属性对吸附过程有着错综复杂的影响。两性离子型 PAC 具有最高的吸附亲和力,而中性 PAC 对土壤疏水性的敏感性更高。平均吸附系数(K)从阴离子磺胺类药物的 0.0915 毫升/克到齐聚物诺氟沙星的 84725.5 毫升/克不等。摩尔体积越大,阳离子 PAC 的吸附力越强,阴离子 PAC 的吸附力越弱。增加溶解度、土壤有机碳、阳离子交换容量、S/L 比值和土壤表面积,同时降低 pH 值、离子强度和温度,都会导致 K 值增加。目前已开发出多种模型来估算 PAC 的 K 值,但这些模型对特定 PAC 和土壤类型的适用性有限。建议今后对 PAC 在土壤中的吸附进行相关研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Environmental Sciences Europe
Environmental Sciences Europe Environmental Science-Pollution
CiteScore
11.20
自引率
1.70%
发文量
110
审稿时长
13 weeks
期刊介绍: ESEU is an international journal, focusing primarily on Europe, with a broad scope covering all aspects of environmental sciences, including the main topic regulation. ESEU will discuss the entanglement between environmental sciences and regulation because, in recent years, there have been misunderstandings and even disagreement between stakeholders in these two areas. ESEU will help to improve the comprehension of issues between environmental sciences and regulation. ESEU will be an outlet from the German-speaking (DACH) countries to Europe and an inlet from Europe to the DACH countries regarding environmental sciences and regulation. Moreover, ESEU will facilitate the exchange of ideas and interaction between Europe and the DACH countries regarding environmental regulatory issues. Although Europe is at the center of ESEU, the journal will not exclude the rest of the world, because regulatory issues pertaining to environmental sciences can be fully seen only from a global perspective.
期刊最新文献
Unlocking the potential of data harmonization and FAIRness in chemical risk assessment: lessons from practice and insights for policy development Heavy metal contamination and potential health risks in upland rice-producing soils of rotational shifting cultivation in northern Thailand Microbial biopesticides are inhibited by honey bee royal jelly and in vitro larval diet COVID-19 pandemic microplastics environmental impacts predicted by deep random forest (DRF) predictive model Is environmental risk assessment possible with the alternatives to acute fish toxicity test? Case study with pharmaceuticals
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1