Advances of the risk factors, immune and inflammation, therapy in postpartum post-traumatic stress disorder

Abstract

Postpartum Post-Traumatic Stress Disorder (PP-PTSD) is a psychological stress disorder that occurs as a result of traumatic childbirth experiences, posing significant risks to the physical and mental well-being of mothers. Although a variety of factors at different stages of the prenatal, traumatic or postnatal may lead to the development of PP-PTSD, the molecular mechanisms are still unclear. Previous studies suggest that immunity and inflammation may play an important role in its mechanism, but there is still a lack of sufficient evidence. As a result, treatment options are very limited. This review aims to provide an overview of recent research advancements in the identification, development, immune / Inflammation, and treatment approaches for PP-PTSD. Overall, PP-PTSD is influenced by multiple factors and has substantial detrimental effects; however, current treatment strategies remain incomplete. Therefore, further research efforts are warranted to ensure timely and effective interventions for a larger number of patients.