Front Cover: Rapidly Diverse Synthesis of N-Aryl-5-Substituted-2-Oxazolidinones via Nucleophilic Epoxide Ring Opening and Intramolecular Acyl Substitution of Epoxy Carbamates (Asian J. Org. Chem. 9/2024)
Nian-Xuan Lin, Shih-Ming Chang, Xin-Shun Chiou, Kelly Lee, Yu-Tung Tsai, Prof. Dr. Cheng-Kun Lin
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引用次数: 0
Abstract
In article number e202400188, Cheng-Kun Lin and co-workers present a method to convert epoxy carbamates to oxazolidinones by combining intermolecular nucleophilic epoxide ring opening with intramolecular acyl substitution in a single step, enabling rapid conversion. It demonstrates favourable reactivity across various aryl groups, benzyl, or tert-butyl carbamates, consistently yielding satisfactory results, with oxazolidinone formation ranging from 55% to 99% across over 24 examples.
期刊介绍:
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.