Artificial intelligence and computer-aided drug discovery: Methods development and application

IF 4.3 3区 生物学 Q1 BIOCHEMICAL RESEARCH METHODS Methods Pub Date : 2024-09-10 DOI:10.1016/j.ymeth.2024.09.005
Haiping Zhang, Yanjie Wei, Konda Mani Saravanan
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来源期刊
Methods
Methods 生物-生化研究方法
CiteScore
9.80
自引率
2.10%
发文量
222
审稿时长
11.3 weeks
期刊介绍: Methods focuses on rapidly developing techniques in the experimental biological and medical sciences. Each topical issue, organized by a guest editor who is an expert in the area covered, consists solely of invited quality articles by specialist authors, many of them reviews. Issues are devoted to specific technical approaches with emphasis on clear detailed descriptions of protocols that allow them to be reproduced easily. The background information provided enables researchers to understand the principles underlying the methods; other helpful sections include comparisons of alternative methods giving the advantages and disadvantages of particular methods, guidance on avoiding potential pitfalls, and suggestions for troubleshooting.
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Refolding-assisted purification of native full-length TDP-43 compatible with BSL-2 safety regulations. Clinical assessment of the diagnostic performance of the LIAISON® Legionella urinary antigen assay. Broad Screening of 2-Styrylchromones Identifies dual inhibitors of the COX-2 pathway. Direct culture is as sensitive as bioassay to achieve in vitro isolation of Toxoplasma gondii from latently infected animal hearts. An Affordable paper based platform for eDNA Filtration, Concentration, and nucleic acid extraction.
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