{"title":"A highly specific red-emitting fluorescent probe for monitoring of Cu2+ in living cells and zebrafish","authors":"Shuai Kong, Yan Zhang, Lianke Xie, Guodong Qi, Yanping Li, Haitao Dai, Qiubo Qi, Yimin Chen","doi":"10.1002/bio.4886","DOIUrl":null,"url":null,"abstract":"<p>A novel seminaphthorhodafluor-based fluorescent probe was designed and prepared. It exhibited an outstanding off–on fluorescence response (about 45-fold enhancement) to Cu<sup>2+</sup> because the structure changed from a spirocyclic form to a ring-open state. It showed satisfactory detection performances for Cu<sup>2+</sup> with fast response speed, high selectivity and anti-interference, and a low detection limit (22.9 nM) due to its long emission wavelength and off–on fluorescence response mode. This probe was also satisfactorily applied for the monitoring of Cu<sup>2+</sup> in living cells and zebrafish.</p>","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Luminescence","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bio.4886","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
A novel seminaphthorhodafluor-based fluorescent probe was designed and prepared. It exhibited an outstanding off–on fluorescence response (about 45-fold enhancement) to Cu2+ because the structure changed from a spirocyclic form to a ring-open state. It showed satisfactory detection performances for Cu2+ with fast response speed, high selectivity and anti-interference, and a low detection limit (22.9 nM) due to its long emission wavelength and off–on fluorescence response mode. This probe was also satisfactorily applied for the monitoring of Cu2+ in living cells and zebrafish.
期刊介绍：
Luminescence provides a forum for the publication of original scientific papers, short communications, technical notes and reviews on fundamental and applied aspects of all forms of luminescence, including bioluminescence, chemiluminescence, electrochemiluminescence, sonoluminescence, triboluminescence, fluorescence, time-resolved fluorescence and phosphorescence. Luminescence publishes papers on assays and analytical methods, instrumentation, mechanistic and synthetic studies, basic biology and chemistry.
Luminescence also publishes details of forthcoming meetings, information on new products, and book reviews. A special feature of the Journal is surveys of the recent literature on selected topics in luminescence.
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