Probing diffusive media through speckle differencing.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Biomedical optics express Pub Date : 2024-08-22 DOI:10.1364/boe.531797
Muralidhar Madabhushi Balaji,Danyal Ahsanullah,Prasanna Rangarajan
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Abstract

Temporally varying speckle patterns, produced by light-matter interaction encode valuable information about inhomogeneities embedded within a scattering medium. These speckle fluctuations arise either from the tuning of the emission frequency of a laser illuminating a static scattering medium or from the microscopic motion of scatterers within a dynamically scattering medium. In this work, we detect embedded inhomogeneities by probing static and dynamic scattering media with coherent light and leveraging the statistical distribution of temporal speckle differences. In addition, we utilize the insights from the speckle differencing paradigm, to present the first experimental results of detecting inhomogeneities embedded within a scattering medium using bio-inspired neuromorphic sensors. The proposed neuromorphic approach simplifies the optical and electronic design, and significantly reduces data throughput by capturing only the differential information in the form of 1-bit spikes.
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通过斑点差分探测扩散介质
由光-物质相互作用产生的时变斑点图案包含了散射介质中不均匀性的宝贵信息。这些斑点波动要么来自激光照射静态散射介质时发射频率的调整,要么来自动态散射介质中散射体的微观运动。在这项工作中,我们用相干光探测静态和动态散射介质,并利用时间斑点差异的统计分布来检测嵌入式不均匀性。此外,我们还利用斑点差分范例的洞察力,首次展示了利用生物启发神经形态传感器检测散射介质中嵌入的非均质性的实验结果。所提出的神经形态方法简化了光学和电子设计,并通过仅捕捉 1 位尖峰形式的差分信息显著降低了数据吞吐量。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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