Pharmacogenomics and pediatric drug development: science and political power. A narrative review

IF 2.5 3区 医学 Q3 PHARMACOLOGY & PHARMACY Expert Opinion on Pharmacotherapy Pub Date : 2024-09-13 DOI:10.1080/14656566.2024.2401429
Earl B. Ettienne, Jane M. Grant-Kels, Pasquale Striano, Emilio Russo, David Neubauer, Klaus Rose
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Abstract

Pharmacogenomics (PGx) investigates how genomes control enzyme expression. Developmental pharmacology (DP) describes the temporal sequence of enzymes impacting absorption, distribution, metabolism,...
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药物基因组学与儿科药物开发:科学与政治权力。叙述性综述
药物基因组学(PGx)研究基因组如何控制酶的表达。发育药理学(DP)描述了影响药物吸收、分布、代谢和代谢的酶的时间序列。
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来源期刊
CiteScore
5.60
自引率
3.10%
发文量
163
审稿时长
4-8 weeks
期刊介绍: Expert Opinion on Pharmacotherapy is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles and original papers on newly approved/near to launch compounds mainly of chemical/synthetic origin, providing expert opinion on the likely impact of these new agents on existing pharmacotherapy of specific diseases.
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