Hippocampal synchronization in a realistic CA1 neuron model

Abstract

This work delves into studying the synchronization in two realistic neuron models using Hodgkin-Huxley dynamics. Unlike simplistic point-like models, excitatory synapses are here randomly distributed along the dendrites, introducing strong stochastic contributions into their signal propagation. To focus on the role of different excitatory positions, we use two copies of the same neuron whose synapses are located at different distances from the soma and are exposed to identical Poissonian distributed current pulses. The synchronization is investigated through a specifically defined spiking correlation function, and its behavior is analyzed as a function of several parameters: inhibition weight, distance from the soma of one synaptic group, excitatory inactivation delay, and weight of the excitatory synapses.