The relationship between endolymphatic hydrops features and hearing loss in Bilateral Meniere's disease

IF 2.4 2区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Head & Face Medicine Pub Date : 2024-09-16 DOI:10.1186/s13005-024-00455-9

Xu Liu, Dan Wang, Yue-Lin Hsieh, Suming Shi, Wuqing Wang

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Abstract

This study aimed to investigate the relationship between the features of endolymphatic hydrops and hearing loss in patients with Bilateral Meniere's Disease. A retrospective analysis was conducted on 77 patients diagnosed with Bilateral Meniere's Disease. The features of endolymphatic hydrops in the affected ear were evaluated through gadolinium-enhanced inner ear Magnetic resonance imaging. The Spearman correlation coefficient, paired t-tests, and Wilcoxon signed-rank tests were employed for data analysis. The analysis revealed a significant correlation between the degree of endolymphatic hydrops and hearing loss across all frequencies(0.125–8 kHz), including the cochlear, vestibular, and overall degree of endolymphatic hydrops. The strongest correlation between the overall degree of endolymphatic hydrops and hearing loss was observed at low frequencies (r = 0.571, p < 0.05), followed by mid-frequencies (r = 0.508, p < 0.05), and high-frequencies (r = 0.351, p < 0.05), with a correlation of r = 0.463, p < 0.05 for the staging of Meniere's disease. Affected Ears with endolymphatic hydrops both in the cochlea and vestibule exhibited more severe hearing loss and Meniere's disease staging compared to those with isolated endolymphatic hydrops within the same patient. The features of endolymphatic hydrops in patients with Bilateral Meniere's Disease were found to correlate with the severity of hearing loss and the staging of Meniere's disease.

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内淋巴水肿特征与双侧梅尼埃病听力损失之间的关系

本研究旨在探讨内淋巴水肿的特征与双侧梅尼埃病患者听力损失之间的关系。研究对 77 名确诊为双侧梅尼埃病的患者进行了回顾性分析。通过钆增强内耳磁共振成像评估了患耳内淋巴水肿的特征。数据分析采用了斯皮尔曼相关系数、配对 t 检验和 Wilcoxon 符号秩检验。分析结果显示，内淋巴水肿程度与所有频率（0.125-8 kHz）的听力损失之间存在明显相关性，包括耳蜗、前庭和内淋巴水肿的总体程度。内淋巴水肿总体程度与听力损失之间的最强相关性出现在低频（r = 0.571，p < 0.05），其次是中频（r = 0.508，p < 0.05）和高频（r = 0.351，p < 0.05），与美尼尔氏病分期的相关性为 r = 0.463，p < 0.05。与同一患者中孤立的内淋巴水肿患者相比，耳蜗和前庭均有内淋巴水肿的患耳表现出更严重的听力损失和美尼尔氏病分期。研究发现，双侧美尼尔氏病患者内淋巴水肿的特征与听力损失的严重程度和美尼尔氏病的分期有关。

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来源期刊

Head & Face Medicine DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.70

自引率

3.30%

发文量

审稿时长

>12 weeks

期刊介绍： Head & Face Medicine is a multidisciplinary open access journal that publishes basic and clinical research concerning all aspects of cranial, facial and oral conditions. The journal covers all aspects of cranial, facial and oral diseases and their management. It has been designed as a multidisciplinary journal for clinicians and researchers involved in the diagnostic and therapeutic aspects of diseases which affect the human head and face. The journal is wide-ranging, covering the development, aetiology, epidemiology and therapy of head and face diseases to the basic science that underlies these diseases. Management of head and face diseases includes all aspects of surgical and non-surgical treatments including psychopharmacological therapies.