Occurrence and Removal Efficiency of Active Pharmaceutical Ingredients (APIs) in Wastewater Treatment Plants: A Systematic Review from Southeast Asia

Yolanda Dwi Astuti, Anindrya Nastiti, Rara D. Larasati, Dwina Roosmini, Muhammad Sonny Abfertiawan
{"title":"Occurrence and Removal Efficiency of Active Pharmaceutical Ingredients (APIs) in Wastewater Treatment Plants: A Systematic Review from Southeast Asia","authors":"Yolanda Dwi Astuti, Anindrya Nastiti, Rara D. Larasati, Dwina Roosmini, Muhammad Sonny Abfertiawan","doi":"10.1021/acsestwater.4c00385","DOIUrl":null,"url":null,"abstract":"Active Pharmaceutical Ingredients (APIs) in the aquatic environment have become a growing concern due to their potential health and environmental impacts. The review aims to examine the occurrence and removal efficiency of APIs in the influent and effluent of wastewater treatment plants (WWTPs) in Southeast Asian countries, including Thailand, Singapore, Malaysia, Indonesia, Vietnam, and the Philippines. The review covers five classes of APIs, i.e., nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, anticonvulsants, antihypertensives, and stimulants. We systematically scoured Scopus-indexed articles published from 2011 to 2022 from Google Scholar, PubMed, and Dimensions and extracted measured concentrations of APIs detected in WWTPs. The wastewater influent contained the following APIs from each class in the highest mean or median concentrations: paracetamol (mean: 26,000 ng/L), ciprofloxacin (mean: 567.4 ng/L), gabapentin (median: up to 3609 ng/L), atenolol (median: up to 4124 ng/L), and caffeine (mean: 38,000 ng/L). Moreover, studies in Singapore have recorded the highest treatment efficiency on various APIs compared to those recorded in Malaysia, Thailand, or Vietnam. This study underscores the importance of implementing standardized monitoring techniques, enhancing wastewater infrastructure, and raising awareness among parties involved to address the environmental hazards linked to pharmaceutical pollution effectively.","PeriodicalId":7078,"journal":{"name":"ACS Es&t Water","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Es&t Water","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1021/acsestwater.4c00385","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Active Pharmaceutical Ingredients (APIs) in the aquatic environment have become a growing concern due to their potential health and environmental impacts. The review aims to examine the occurrence and removal efficiency of APIs in the influent and effluent of wastewater treatment plants (WWTPs) in Southeast Asian countries, including Thailand, Singapore, Malaysia, Indonesia, Vietnam, and the Philippines. The review covers five classes of APIs, i.e., nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, anticonvulsants, antihypertensives, and stimulants. We systematically scoured Scopus-indexed articles published from 2011 to 2022 from Google Scholar, PubMed, and Dimensions and extracted measured concentrations of APIs detected in WWTPs. The wastewater influent contained the following APIs from each class in the highest mean or median concentrations: paracetamol (mean: 26,000 ng/L), ciprofloxacin (mean: 567.4 ng/L), gabapentin (median: up to 3609 ng/L), atenolol (median: up to 4124 ng/L), and caffeine (mean: 38,000 ng/L). Moreover, studies in Singapore have recorded the highest treatment efficiency on various APIs compared to those recorded in Malaysia, Thailand, or Vietnam. This study underscores the importance of implementing standardized monitoring techniques, enhancing wastewater infrastructure, and raising awareness among parties involved to address the environmental hazards linked to pharmaceutical pollution effectively.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
污水处理厂中活性药物成分 (API) 的存在和去除效率:来自东南亚的系统性综述
由于其对健康和环境的潜在影响,水生环境中的活性药物成分 (API) 日益受到关注。本综述旨在研究东南亚国家(包括泰国、新加坡、马来西亚、印度尼西亚、越南和菲律宾)废水处理厂(WWTPs)进水和出水中原料药的发生率和去除效率。综述涵盖五类原料药,即非甾体抗炎药 (NSAID)、抗生素、抗惊厥药、抗高血压药和兴奋剂。我们从 Google Scholar、PubMed 和 Dimensions 系统地搜索了 2011 年至 2022 年期间发表的 Scopus 索引文章,并提取了污水处理厂中检测到的原料药的测量浓度。废水废水中含有以下平均浓度或中位浓度最高的各类原料药:扑热息痛(平均:26,000 纳克/升)、环丙沙星(平均:567.4 纳克/升)、加巴喷丁(中位数:高达 3609 纳克/升)、阿替洛尔(中位数:高达 4124 纳克/升)和咖啡因(平均:38,000 纳克/升)。此外,与马来西亚、泰国或越南的研究相比,新加坡对各种原料药的治疗效率最高。这项研究强调了实施标准化监测技术、加强废水处理基础设施以及提高相关各方的意识对于有效解决与制药污染相关的环境危害的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
The Evolution Mechanism of the Water Supply System in the Water Receiving Area of a Water Diversion Project Inspired by Dissipative Structure Theory Defect Engineered 2D Graphitic Carbon Nitride for Photochemical, (Bio)Electrochemical, and Microplastic Remediation Advancements Facile Synthesis of ZIF-67-Incorporated Electrospun PVA Nanofibers Composite for Efficient Pb (II) Adsorption from Water: Docking and Experimental Studies Occurrence and Removal Efficiency of Active Pharmaceutical Ingredients (APIs) in Wastewater Treatment Plants: A Systematic Review from Southeast Asia Electrochemical In Situ Production of Magnetite for the Removal of Se from Wastewater
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1