Giulia Rotunno, Julia Deinsberger, Kristen M. Meiburger, Lisa Krainz, Lukasz Bugyi, Valentin Hacker, Richard Haindl, Rainer Leitgeb, Christoph Sinz, Leopold Schmetterer, Wolfgang Drexler, Benedikt Weber, Mengyang Liu
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引用次数: 0
Abstract
Chronic venous insufficiency (CVI) is a global health concern with significant public health and individual impact. Currently available diagnostic methods cannot visualize microvenous pathologies that have shown to result in severe forms of CVI and also affect the skin. Optical coherence tomography angiography (OCTA) may close the CVI diagnostic gap by providing a fast, label-free, and non-invasive solution to visualize cutaneous microvasculature. The study enlisted 66 subjects, including 53 CVI patients spanning all clinical-etiology-anatomic-pathophysiologic (CEAP) C stages and 13 healthy controls. The high spatial resolution OCTA system used was specifically designed for skin imaging. Significant microangiographic pattern variations emerged, both in qualitative and quantitative terms. OCTA provided valuable insights into cutaneous microvascular changes among different CVI stages. Thereby, OCTA may enable the selection of patient populations at risk for disease progression in the future.
期刊介绍:
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