Preparation of magnetic scaffolds via supercritical carbon dioxide foaming process using iron oxide nanoparticles coated with CO2-philic materials as nucleating agents

IF 2.7 3区 化学 Q2 POLYMER SCIENCE Journal of Applied Polymer Science Pub Date : 2024-09-17 DOI:10.1002/app.56256
Zhen Jiao, Shuo Zhang, Jinjing Wang, Yi Zhang
{"title":"Preparation of magnetic scaffolds via supercritical carbon dioxide foaming process using iron oxide nanoparticles coated with CO2-philic materials as nucleating agents","authors":"Zhen Jiao,&nbsp;Shuo Zhang,&nbsp;Jinjing Wang,&nbsp;Yi Zhang","doi":"10.1002/app.56256","DOIUrl":null,"url":null,"abstract":"<p>The iron oxide nanoparticles (IONs), coated with different materials, are synthesized and utilized as nucleating agents to prepare magnetic multi-modal porous scaffolds of poly (lactic-<i>co</i>-glycolic acid)/IONs using the supercritical carbon dioxide (ScCO<sub>2</sub>) foaming process. The effects of the modification materials, including citric acid, polycaprolactone, and polyvinyl acetate, on the foaming process and properties of the magnetic scaffolds are systematically investigated. The results indicate that the solubility and diffusion ability of CO<sub>2</sub> in the foaming materials played a vital role in the foaming process. The use of CO<sub>2</sub>-philic materials and high pressure proves beneficial in generating micropores. The scaffolds with multi-modal porous structures can be obtained at relatively low pressure for the ScCO<sub>2</sub> foaming systems evaluated in this study. Furthermore, the prepared scaffolds exhibit high porosity and a good compressive modulus (higher than 0.4 MPa), satisfying the requirements of tissue engineering for soft tissue scaffolds.</p>","PeriodicalId":183,"journal":{"name":"Journal of Applied Polymer Science","volume":"141 47","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Polymer Science","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/app.56256","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0

Abstract

The iron oxide nanoparticles (IONs), coated with different materials, are synthesized and utilized as nucleating agents to prepare magnetic multi-modal porous scaffolds of poly (lactic-co-glycolic acid)/IONs using the supercritical carbon dioxide (ScCO2) foaming process. The effects of the modification materials, including citric acid, polycaprolactone, and polyvinyl acetate, on the foaming process and properties of the magnetic scaffolds are systematically investigated. The results indicate that the solubility and diffusion ability of CO2 in the foaming materials played a vital role in the foaming process. The use of CO2-philic materials and high pressure proves beneficial in generating micropores. The scaffolds with multi-modal porous structures can be obtained at relatively low pressure for the ScCO2 foaming systems evaluated in this study. Furthermore, the prepared scaffolds exhibit high porosity and a good compressive modulus (higher than 0.4 MPa), satisfying the requirements of tissue engineering for soft tissue scaffolds.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
使用涂有亲二氧化碳材料的氧化铁纳米颗粒作为成核剂,通过超临界二氧化碳发泡工艺制备磁性支架
利用超临界二氧化碳(ScCO2)发泡工艺,合成了包覆不同材料的氧化铁纳米粒子(IONs),并将其作为成核剂用于制备聚(乳酸-共聚乙醇酸)/IONs 的磁性多模多孔支架。系统研究了柠檬酸、聚己内酯和聚醋酸乙烯等改性材料对发泡过程和磁性支架性能的影响。结果表明,二氧化碳在发泡材料中的溶解度和扩散能力对发泡过程起着至关重要的作用。亲二氧化碳材料和高压的使用有利于产生微孔。在本研究评估的 ScCO2 发泡系统中,可以在相对较低的压力下获得具有多模多孔结构的支架。此外,制备的支架具有高孔隙率和良好的压缩模量(高于 0.4 兆帕),满足了组织工程对软组织支架的要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Applied Polymer Science
Journal of Applied Polymer Science 化学-高分子科学
CiteScore
5.70
自引率
10.00%
发文量
1280
审稿时长
2.7 months
期刊介绍: The Journal of Applied Polymer Science is the largest peer-reviewed publication in polymers, #3 by total citations, and features results with real-world impact on membranes, polysaccharides, and much more.
期刊最新文献
Editorial Board, Aims & Scope, Table of Contents Editorial Board, Aims & Scope, Table of Contents Editorial Board, Aims & Scope, Table of Contents Synthesis of reaction promoters for epoxy polymerization: Enhancing storage stability and mechanical properties of one-pot epoxy systems Editorial Board, Aims & Scope, Table of Contents
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1