Does patient-specific instrument or robot improve imaging and functional outcomes in unicompartmental knee arthroplasty? A bayesian analysis

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-09-19 DOI:10.1007/s00402-024-05569-y
Xufeng Jiao, Mincong Du, Qi Li, Cheng Huang, Ran Ding, Weiguo Wang
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Abstract

Introduction

This study conducted a Bayesian network meta-analysis (NMA) to compare the imaging and functional outcomes of patient-specific instrument-assisted unicompartmental knee arthroplasty (P-UKA), robot-assisted unicompartmental knee arthroplasty (R-UKA), and conventional unicompartmental knee arthroplasty (C-UKA).

Materials and methods

A comprehensive search was performed on five electronic databases and major orthopedic journals as of September 24, 2023. We included randomized controlled studies featuring at least two interventions of P-UKA, R-UKA, or C-UKA. Primary outcomes encompassed the deviation angle of hip-knee-ankle angle, as well as the coronal and sagittal plane alignment of femoral and tibial components. Secondary outcomes included patient-reported outcome measures (PROM), surgery time, revision rate, and complication rate. Bayesian framework was employed for risk ratio (RR) or mean deviation (MD) analysis, and treatment hierarchy was established based on rank probabilities.

Results

This NMA included 871 knees from 12 selected studies. In sagittal plane, R-UKA exhibited a significantly reduced deviation angle of femoral component compared to P-UKA (MD: 4.16, 95% CI: 0.21, 8.07), and of tibial component in comparison to C-UKA (MD: -2.45, 95% CI: -4.20, -0.68). Notably, the surgery time was significantly longer in R-UKA than in C-UKA (MD: 15.98, 95% CI: 3.11, 28.88). However, no significant differences were observed in other outcomes.

Conclusion

Compared with P-UKA or C-UKA, R-UKA significantly improves the femoral and tibial component alignment in the sagittal plane, although this does not translate into discernible differences in functional outcomes. Comprehensive considerations of economic and learning costs are imperative for the judicious selection of the appropriate procedure.

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患者专用器械或机器人能否改善单间室膝关节置换术的成像和功能结果?贝叶斯分析
导言本研究进行了贝叶斯网络荟萃分析(NMA),以比较患者特异性器械辅助单间室膝关节置换术(P-UKA)、机器人辅助单间室膝关节置换术(R-UKA)和传统单间室膝关节置换术(C-UKA)的成像和功能结果。材料与方法截至 2023 年 9 月 24 日,我们对五个电子数据库和主要骨科期刊进行了全面检索。我们纳入的随机对照研究至少包含 P-UKA、R-UKA 或 C-UKA 的两种干预方法。主要结果包括髋关节-膝关节-踝关节角度偏差,以及股骨和胫骨组件的冠状面和矢状面对齐情况。次要结果包括患者报告结果指标(PROM)、手术时间、翻修率和并发症发生率。采用贝叶斯框架进行风险比(RR)或平均偏差(MD)分析,并根据等级概率确定治疗等级。在矢状面上,R-UKA 与 P-UKA 相比,股骨构件的偏差角度显著减少(MD:4.16,95% CI:0.21,8.07),与 C-UKA 相比,胫骨构件的偏差角度显著减少(MD:-2.45,95% CI:-4.20,-0.68)。值得注意的是,R-UKA的手术时间明显长于C-UKA(MD:15.98,95% CI:3.11,28.88)。结论与 P-UKA 或 C-UKA 相比,R-UKA 能显著改善股骨和胫骨组件在矢状面上的对位,但这并不能转化为功能结果上的明显差异。综合考虑经济和学习成本是明智选择合适手术的必要条件。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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