{"title":"Clinical significance and biological role of claudin-1 in oral squamous cell carcinoma cells","authors":"Tadayoshi Nobumoto DDS PhD, Sachiko Yamasaki DDS PhD, Atsuko Hamada DDS PhD, Mirai Higaki DDS PhD, Nanako Ito DDS PhD, Fumitaka Obayashi DDS PhD, Yasutaka Ishida DDS PhD, Tomoaki Hamana DDS PhD, Tomoaki Shintani DDS PhD, Ryouji Tani DDS PhD, Koichi Koizumi DDS PhD, Souichi Yanamoto DDS PhD, Yasutaka Hayashido DDS PhD","doi":"10.1016/j.oooo.2024.08.020","DOIUrl":null,"url":null,"abstract":"Claudin (CLD), a major component of tight junctions, is a four-transmembrane protein, and 24 subtypes have been reported in humans. CLD expression is highly tissue-specific; CLD1 has been reported to be expressed in the skin and mucosa. There have been few reports on CLD1 expression and its function in oral cancer.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.oooo.2024.08.020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Claudin (CLD), a major component of tight junctions, is a four-transmembrane protein, and 24 subtypes have been reported in humans. CLD expression is highly tissue-specific; CLD1 has been reported to be expressed in the skin and mucosa. There have been few reports on CLD1 expression and its function in oral cancer.
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