Injectable therapeutic peptides-an adjunct to regenerative medicine and sports performance?

Mikalyn T DeFoor,Travis J Dekker
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Abstract

High level athletes and bodybuilders are constantly seeking novel therapies to enhance recovery and expedite return from injury-injectable peptides are a new and trending therapy that may be the wave of the future of in the realm of regenerative medicine research in treating joint injuries and osteoarthritis. Very early in vivo research of the pharmacokinetics suggests the possibility of Body Protection Compound 157 (BPC-157) appears to be at the forefront of therapeutic peptides with early demonstration of these experimental peptides optimizing endurance training, metabolism, recovery and tissue repair. While uUnregulated, yetand readily available for purchase over the internet, there is scarce orthopaedic literature investigating the clinical use and outcomes of these therapeutic peptides in tendon, muscle and cartilage injury. However, this has not slowed the recent exponential growth of the multi-billion-dollar industry in development of therapeutic peptides. As orthopaedic surgeons and team physicians, we should stay up-to-date with the latest pharmacokinetic, safety, ethical, and legal profilesregulations regarding synthetic peptide supplementation for injury recovery and sports performance optimization from our elite athletes to our fitness fanatics as these patients will continue to seek the latest and greatest in treatment options and will be approaching us with questions on their results, risks and benefits..
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注射治疗肽--再生医学和运动表现的辅助手段?
高水平运动员和健美运动员一直在寻求新的疗法,以促进恢复和加快伤后康复--注射肽是一种新的趋势性疗法,可能成为再生医学研究领域治疗关节损伤和骨关节炎的未来趋势。早期的体内药代动力学研究表明,人体保护化合物 157(BPC-157)似乎走在了治疗肽的最前沿,这些实验性肽可优化耐力训练、新陈代谢、恢复和组织修复。虽然这些治疗肽不受管制,而且可以在互联网上随时购买,但很少有骨科文献研究这些治疗肽在肌腱、肌肉和软骨损伤中的临床应用和效果。然而,这并没有减缓最近数十亿美元的治疗肽开发产业的指数级增长。作为骨科外科医生和队医,我们应该随时了解有关合成肽补充剂用于损伤恢复和运动表现优化的最新药代动力学、安全性、道德和法律规定,从我们的精英运动员到我们的健身狂热者,因为这些患者将继续寻求最新和最好的治疗方案,并会带着有关其效果、风险和益处的问题来找我们。
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