Drug overdose deaths during prison riots and mental states of prisoners: a case study

IF 3.2 3区 医学 Q2 PSYCHIATRY Frontiers in Psychiatry Pub Date : 2024-09-13 DOI:10.3389/fpsyt.2024.1377995
Luca Tomassini, Gianni Giuli, Edoardo Bottoni, Maria Chiara David, Roberto Scendoni
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Abstract

Prison riots, though often sensationalized in the media, have profound consequences, with a significant death toll. Prison populations, historically plagued by psychiatric disorders, witness high rates of suicide, particularly linked to turbulent events like riots. This study examines three drug overdose deaths resulting from a prison riot during the initial wave of the SARS-CoV-2 pandemic in Italy. To ascertain the nature of these deaths, a comprehensive toxicological analysis was conducted. Immunochemical screening and gas chromatography-mass spectrometry were employed to detect a spectrum of drugs, including MDMA, methadone, morphine, cannabis derivatives, benzodiazepines, and others. The toxicological findings revealed high concentrations of various substances in the biological fluids of the deceased inmates. Tramadol and mirtazapine were implicated in one case, while methadone was a common factor in the deaths of two inmates, one of whom also ingested diazepam. The synergistic effects of substances were explored, with methadone identified as a leading cause of death in two cases. Prison riots exacerbate drug abuse issues within prisons, leading to mass intoxication and overdose, as witnessed in historic incidents globally. The study underscores the challenges in determining whether such deaths are accidental, intentional (suicidal), or a consequence of uncontrollable drug consumption during a riot. The prison environment also amplifies pre-existing psychiatric disorders, and incidents like riots can trigger a cascade of uncontrollable psychological reactions. The three potential scenarios are drug dependence, accidental overdose in recreational drug use, and suicide attempts through substance ingestion.
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监狱骚乱期间吸毒过量致死与囚犯的精神状态:案例研究
监狱暴乱虽然经常被媒体大肆渲染,但其后果却十分严重,造成大量人员死亡。监狱服刑人员历来饱受精神疾病的困扰,他们的自杀率很高,尤其与暴乱等动荡事件有关。本研究探讨了意大利 SARS-CoV-2 大流行初期监狱暴乱导致的三起吸毒过量死亡事件。为了确定这些死亡事件的性质,我们进行了全面的毒理学分析。采用免疫化学筛选和气相色谱-质谱法检测了一系列药物,包括亚甲二氧基甲基苯丙胺、美沙酮、吗啡、大麻衍生物、苯二氮卓等。毒理学研究结果表明,已故囚犯的生物体液中含有高浓度的各种物质。曲马多和米氮平与一起案件有关,而美沙酮是造成两名囚犯死亡的共同因素,其中一人还摄入了地西泮。对药物的协同作用进行了探讨,在两起案件中,美沙酮被确定为主要死因。监狱暴乱加剧了监狱内的药物滥用问题,导致大规模中毒和用药过量,这在全球历史性事件中都有发生。这项研究强调了在确定此类死亡是意外、故意(自杀)还是骚乱期间无法控制的毒品消费造成的后果方面所面临的挑战。监狱环境也会放大原有的精神障碍,暴乱等事件会引发一连串无法控制的心理反应。三种可能的情况是药物依赖、娱乐性吸毒意外过量以及通过药物摄入企图自杀。
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来源期刊
Frontiers in Psychiatry
Frontiers in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
6.20
自引率
8.50%
发文量
2813
审稿时长
14 weeks
期刊介绍: Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.
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