Determinant of 30-day Mortality of Pulmonary Legionellosis: Do Co-Infections Matter?

IF 3.8 4区 医学 Q2 IMMUNOLOGY Open Forum Infectious Diseases Pub Date : 2024-09-13 DOI:10.1093/ofid/ofae529
Takahiro Matsuo, Sebastian Wurster, Ying Jiang, Jeffrey Tarrand, Scott E Evans, Dimitrios P Kontoyiannis
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Abstract

We retrospectively reviewed 64 cancer patients with pulmonary legionellosis (Legionella pneumophila in 73%). Nearly all patients received Legionella-active antibiotics, yet 30-day mortality was 23%. Independent predictors of 30-day mortality were hyponatremia, bilateral lung involvement, and SOFA score ≥5. Lung co-infections were common (31%) but did not significantly increase mortality.
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肺军团菌病 30 天死亡率的决定因素:合并感染重要吗?
我们对 64 名患肺军团菌病的癌症患者(73% 患有嗜肺军团菌病)进行了回顾性研究。几乎所有患者都接受了军团菌活性抗生素治疗,但 30 天死亡率为 23%。低钠血症、双肺受累和 SOFA 评分≥5 分是预测 30 天死亡率的独立因素。肺部合并感染很常见(31%),但并不会显著增加死亡率。
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来源期刊
Open Forum Infectious Diseases
Open Forum Infectious Diseases Medicine-Neurology (clinical)
CiteScore
6.70
自引率
4.80%
发文量
630
审稿时长
9 weeks
期刊介绍: Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.
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