M. V. Goryaeva, M. A. Ezhikova, Ya. V. Burgart, M. S. Kustova, M. I. Kodess, P. A. Slepukhin, V. I. Saloutin
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引用次数: 0
Abstract
A characteristic feature of the three-component cyclization of ethyl trifluoropyruvate and methyl ketones with 1,3-diamino-2-propanol is the formation of 8a-alkyl(phenyl)-3,7-dihydroxy-7-(trifluoromethyl)hexahydropyrrolo[1,2-a]pyrimidin-6(2H)-ones as one, two, or three diastereomers, depending on the methyl ketone component. The structures of the new heterocycles were established using the data of X-ray diffraction and 1H and 13C NMR spectra, including 2D 1H—13C HSQC, HMBC, 1H—1H COSY, and NOESY experiments.
期刊介绍：
Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections:
General and Inorganic Chemistry;
Physical Chemistry;
Organic Chemistry;
Organometallic Chemistry;
Chemistry of Natural Compounds and Bioorganic Chemistry.
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