Management of triggering factor effects in sensitive skin syndrome with a dermo‐cosmetic product

IF 2.3 4区 医学 Q2 DERMATOLOGY Journal of Cosmetic Dermatology Pub Date : 2024-09-18 DOI:10.1111/jocd.16529
Helena Polena, Arnaud Fontbonne, Elise Abric, Guillaume Lecerf, Marlène Chavagnac‐Bonneville, Alain Moga, Nathalie Ardiet, Sandra Trompezinski, Michèle Sayag
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Abstract

ObjectiveEnvironmental factors are important in the generation or aggravation of sensitive skin syndrome (SSS). Creams can be useful for patients with SSS, particularly when triggering factors cannot be avoided. Several clinical studies have investigated the safety and efficacy of specific creams in patients with SSS, but the majority were assessed with a single type of triggering factor and were non‐comparative. Therefore, this study's aim was to investigate, the benefit of a specific dermo‐cosmetic product in response to physical and chemical factors in subjects with SSS.MethodsThree clinical studies were performed on subjects presenting SSS. The physical impact was assessed in a stripping test, and in a randomized intra‐individual study with a newly developed heat–cold stress model. To assess chemical factors, a capsaicin test on the nasolabial fold was performed.ResultsThe product significantly reduced the increase in skin microcirculation caused by stripping after 30 min versus. The untreated condition (45.8% vs. 62.0%; p < 0.01). Immediately and at D28, the product induced a significant increase in skin hydration even after a heat–cold stress, while the overall score of unpleasant symptoms significantly decreased compared with the control (8.1 vs. 10.7 and 3.7 vs. 8.0, respectively; p < 0.01). Regarding chemical factors, a significant difference in the sensation intensity (p < 0.001) was observed after capsaicin stress, also in terms of the sensation duration due to the product application versus the control (192 s vs. 403 s; p < 0.001).ConclusionThese studies show that topical application of a dermo‐cosmetic product can prevent unpleasant symptoms and improve the skin state in SSS exposed to physical and chemical triggering factors.
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用皮肤美容产品控制敏感性皮肤综合征的诱发因素效应
目标环境因素是导致敏感性皮肤综合症(SSS)产生或加重的重要原因。药膏对 SSS 患者很有用,尤其是在无法避免诱发因素的情况下。有几项临床研究调查了特定药膏对 SSS 患者的安全性和疗效,但大多数研究都是针对单一类型的诱发因素进行评估,不具有可比性。因此,本研究旨在调查特定皮肤美容产品对 SSS 患者的物理和化学因素的益处。方法对出现 SSS 的受试者进行了三项临床研究。物理影响通过剥离试验和使用新开发的冷热应激模型进行的随机个体内研究进行评估。为了评估化学因素,对鼻唇沟进行了辣椒素试验。与未处理的情况相比(45.8% 对 62.0%;p <;0.01)。即使在冷热应激后,该产品也能立即和在第 28 天显著增加皮肤的水合作用,同时与对照组相比,不愉快症状的总分显著降低(分别为 8.1 vs. 10.7 和 3.7 vs. 8.0;p <;0.01)。结论:这些研究表明,在暴露于物理和化学诱发因素的 SSS 中,局部使用皮肤美容产品可以预防不适症状并改善皮肤状态。
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来源期刊
CiteScore
4.30
自引率
13.00%
发文量
818
审稿时长
>12 weeks
期刊介绍: The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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