Numerical simulations of a two-strain dengue model to investigate the efficacy of the deployment of Wolbachia-carrying mosquitoes and vaccination for reducing the incidence of dengue infections
{"title":"Numerical simulations of a two-strain dengue model to investigate the efficacy of the deployment of Wolbachia-carrying mosquitoes and vaccination for reducing the incidence of dengue infections","authors":"","doi":"10.1016/j.jobb.2024.08.003","DOIUrl":null,"url":null,"abstract":"<div><p>This study investigated the usefulness of a two-serotype dengue mathematical model to gain insights into the effects of antibody-dependent enhancement and temperature on dengue transmission dynamics in the presence of vaccination and <em>Wolbachia</em>-carrying mosquitoes. In particular, the effects of temperature on the mosquito death and maturation rates in secondary infections were examined. A deterministic mathematical model was formulated and analysed to address this problem. The results suggest that controlling the population of aquatic mosquitoes is appropriate for reducing the incidence of secondary infections. Furthermore, the <em>wAu Wolbachia</em> strain was more effective in reducing secondary infections.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2588933824000487/pdfft?md5=c755ea23a43690b6930ae1a984285d28&pid=1-s2.0-S2588933824000487-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biosafety and Biosecurity","FirstCategoryId":"1093","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2588933824000487","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Social Sciences","Score":null,"Total":0}
引用次数: 0
Abstract
This study investigated the usefulness of a two-serotype dengue mathematical model to gain insights into the effects of antibody-dependent enhancement and temperature on dengue transmission dynamics in the presence of vaccination and Wolbachia-carrying mosquitoes. In particular, the effects of temperature on the mosquito death and maturation rates in secondary infections were examined. A deterministic mathematical model was formulated and analysed to address this problem. The results suggest that controlling the population of aquatic mosquitoes is appropriate for reducing the incidence of secondary infections. Furthermore, the wAu Wolbachia strain was more effective in reducing secondary infections.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
